SPSIPB vs ESPB Block for Breast Surgery Pain
Summary
NIH registered ClinicalTrials.gov Study NCT07541040, a prospective randomized assessor-blinded trial comparing serratus posterior superior intercostal plane block (SPSIPB) and erector spinae plane block (ESPB) for postoperative analgesia in unilateral breast surgery. 54 patients will be randomized to receive either intervention before general anesthesia. Primary outcome is postoperative pain scores within 24 hours; secondary outcome is opioid consumption.
What changed
NIH registered ClinicalTrials.gov Study NCT07541040, a prospective randomized controlled trial comparing two regional anesthesia techniques for breast surgery. The study will enroll 54 patients randomized to receive either serratus posterior superior intercostal plane block (SPSIPB) or erector spinae plane block (ESPB) prior to general anesthesia. No regulatory obligations or compliance requirements are imposed by this registration. Clinical investigators and anesthesiology departments conducting similar regional anesthesia research should note the comparative endpoints (pain scores and opioid consumption) as standard outcome measures for this procedure class.
Archived snapshot
Apr 22, 2026GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.
Serratus vs ESP Block for Postoperative Pain in Unilateral Breast Surgery: A Randomized Study
N/A NCT07541040 Kind: NA Apr 21, 2026
Abstract
This prospective, randomized, assessor-blinded trial compares serratus posterior superior intercostal plane block (SPSIPB) and erector spinae plane block (ESPB) for postoperative analgesia in unilateral breast surgery. 54 patients will be randomized to receive either SPSIPB or ESPB before general anesthesia.
The primary outcome is postoperative pain scores within the first 24 hours. The secondary outcome is opioid consumption.
Conditions: Post Operative Pain, Opioid Use
Interventions: Serratus Posterior Superior Intercostal Plane Block
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