Small Molecule Protein Synthesis Modulators
Summary
The USPTO published patent application US20260109696A1 assigned to Interdict Bio, Inc., filed September 19, 2025 (Application No. 19333657), covering small molecule compounds and pharmaceutical compositions useful for modulating protein synthesis. The disclosed compounds and methods are directed to treating diseases or disorders associated with BCL-2, MYC, CCND1, MCL-1, ALK, and KRAS-G12D targets.
“The present disclosure provides compounds, and pharmaceutically acceptable salts thereof, which are useful for modulating protein synthesis.”
About this source
USPTO classification C07D covers heterocyclic organic compounds: the chemical core of most small-molecule drugs, including kinase inhibitors, GLP-1 receptor agonists, antibiotics, antivirals, and CNS therapies. Every newly published application in C07D lands in this feed, around 160 a month. Applications publish 18 months after filing, so this feed reveals what medicinal chemistry groups at Pfizer, Novartis, Roche, Shionogi, and others were synthesizing in the prior year and a half. Watch this if you run a medicinal chemistry program, file patent clearance for new drug candidates, scout competitor pipelines before clinical readouts, or track heterocyclic innovation across therapeutic areas.
What changed
The USPTO published patent application US20260109696A1 for small molecule protein synthesis modulators, filed by Interdict Bio, Inc. on September 19, 2025. The application discloses compounds and pharmaceutical compositions useful for modulating protein synthesis, along with methods of treating diseases or disorders associated with specified molecular targets including BCL-2, MYC, CCND1, MCL-1, ALK, and KRAS-G12D.
Pharmaceutical companies and researchers working in oncology and targeted protein degradation may need to assess whether their own compound portfolios or research programs overlap with the claimed subject matter, particularly for therapies addressing the specified cancer-related molecular targets.
Archived snapshot
Apr 23, 2026GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.
SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS
Application US20260109696A1 Kind: A1 Apr 23, 2026
Assignee
Interdict Bio, Inc.
Inventors
Sogole Sami Bahmanyar, Lawrence Hamann, Zef Konst, David Gygi, Margot Meyers
Abstract
The present disclosure provides compounds, and pharmaceutically acceptable salts thereof, which are useful for modulating protein synthesis. The present disclosure also provides pharmaceutical compositions and kits comprising the compounds, or pharmaceutically acceptable salts thereof, and methods of treating or preventing diseases or disorders (e.g., diseases or disorders associated with BCL-2, MYC, CCND1, MCL-1, ALK, KRAS-G12D) by administering to a subject in need thereof the compounds, or pharmaceutically acceptable salts thereof, or pharmaceutical compositions thereof.
CPC Classifications
C07D 417/14 A61K 31/40 A61K 31/4025 A61K 31/404 A61K 31/4155 A61K 31/416 A61K 31/4192 A61K 31/4196 A61K 31/422 A61K 31/427 A61K 31/4439 A61K 31/501 A61K 31/517 C07D 207/12 C07D 401/10 C07D 401/14 C07D 403/10 C07D 403/12 C07D 405/14 C07D 413/10 C07D 413/14 C07D 417/10 C07D 495/04 C07D 513/04
Filing Date
2025-09-19
Application No.
19333657
Parties
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