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Engineered Microorganisms With Enhanced Protein Expression

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Summary

The USPTO published patent application US20260109937A1 filed by Nathan Crook, Deniz Durmusoglu, Ibrahim Al'Abri, and Daniel Haller on September 22, 2023, covering genetically modified microorganisms engineered for enhanced production and secretion of peptides and polypeptides. The application specifically discloses yeast cells engineered with improved protein expression capabilities, with CPC classifications including C12N 1/18, C12N 9/90, and related biotechnology codes.

“The present disclosure provides materials and methods related to the production of peptides and polypeptides from engineered microorganisms.”

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About this source

GovPing monitors USPTO Patent Applications - Biotech (C12N) for new healthcare & life sciences regulatory changes. Every update since tracking began is archived, classified, and available as free RSS or email alerts — 236 changes logged to date.

What changed

The USPTO published a new patent application disclosing engineered microorganisms, specifically yeast cells, with genetically enhanced protein expression and secretion capabilities. The application names four inventors and was originally filed on September 22, 2023 under Application No. 19114168.

For biotechnology and pharmaceutical companies engaged in recombinant protein production, this patent application indicates competitive activity in the field of engineered yeast expression systems. Companies developing similar microbial expression platforms should review their own IP positions and freedom-to-operate status. The application does not impose compliance obligations but signals ongoing innovation in this technical space.

Archived snapshot

Apr 23, 2026

GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.

← USPTO Patent Applications

ENGINEERED MICROORGANISMS WITH ENHANCED PROTEIN EXPRESSION AND SECRETION

Application US20260109937A1 Kind: A1 Apr 23, 2026

Inventors

Nathan Crook, Deniz Durmusoglu, Ibrahim Al'Abri, Daniel Haller

Abstract

The present disclosure provides materials and methods related to the production of peptides and polypeptides from engineered microorganisms. In particular, the present disclosure provides compositions and methods for producing a genetically modified microorganism (e.g., yeast cell) with enhanced protein expression and/or secretion.

CPC Classifications

C12N 1/18 C12N 9/90 C07K 2319/036 C12R 2001/85 C12Y 504/02007

Filing Date

2023-09-22

Application No.

19114168

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Last updated

Classification

Agency
USPTO
Published
April 23rd, 2026
Instrument
Notice
Branch
Executive
Legal weight
Non-binding
Stage
Final
Change scope
Minor
Docket
19114168

Who this affects

Applies to
Drug manufacturers Pharmaceutical companies
Industry sector
3254.1 Biotechnology
Activity scope
Patent application Recombinant protein production Microbial engineering
Geographic scope
United States US

Taxonomy

Primary area
Intellectual Property
Operational domain
Legal
Topics
Biotechnology Pharmaceuticals

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