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Pelthos Therapeutics Injectable Extended-Release Formulation for Pain Treatment

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Summary

USPTO published patent application US20260108499A1 for Pelthos Therapeutics Inc., filed October 22, 2025, covering injectable pharmaceutical formulations for extended release comprising 2-{[3-(5-chloro-2-{2-chloro-5-fluoro-4-[(1,3-thiazol-4-yl)sulfamoyl]phenoxy}phenyl)propyl]amino}acetamide, or a pharmaceutically acceptable salt thereof. The named inventors are Eric D. LANG, Simon Paul CHANDLER, Deshou JIANG, and Richard MALAMUT (Application No. 19365336). The formulations are intended for treatment of pain or providing peri-operative anesthesia or post-operative analgesia.

“The present invention relates to pharmaceutical formulations comprising 2-{[3-(5-chloro-2-{2-chloro-5-fluoro-4-[(1,3-thiazol-4-yl)sulfamoyl]phenoxy}phenyl)propyl]amino}acetamide, or a pharmaceutically acceptable salt thereof, for extended release, to methods for preparation thereof, and to uses thereof for treatment of pain or providing peri-operative anesthesia or post-operative analgesia.”

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About this source

GovPing monitors USPTO Patent Applications - Therapeutics (A61P) for new healthcare & life sciences regulatory changes. Every update since tracking began is archived, classified, and available as free RSS or email alerts — 203 changes logged to date.

What changed

USPTO published patent application US20260108499A1 assigned to Pelthos Therapeutics Inc., covering injectable pharmaceutical formulations for extended release. The formulations comprise 2-{[3-(5-chloro-2-{2-chloro-5-fluoro-4-[(1,3-thiazol-4-yl)sulfamoyl]phenoxy}phenyl)propyl]amino}acetamide, or a pharmaceutically acceptable salt thereof. CPC classifications span A61K 9/0019, A61K 9/06, A61K 9/08, A61K 9/5031, A61K 47/02, A61K 47/10, A61K 47/14, A61K 47/24, A61K 47/32, A61K 47/38, A61K 47/44, and A61P 25/04.

For pharmaceutical companies and investors monitoring the competitive landscape, this published application signals Pelthos Therapeutics' entry into the extended-release injectable pain treatment space. While the patent is still pending, competitors developing similar formulations for peri-operative anesthesia or post-operative analgesia should assess their own IP positions against the compound claims disclosed. Generic or biosimilar manufacturers should evaluate whether alternative delivery technologies could achieve similar therapeutic outcomes without infringement.

Archived snapshot

Apr 23, 2026

GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.

← USPTO Patent Applications

INJECTABLE FORMULATIONS

Application US20260108499A1 Kind: A1 Apr 23, 2026

Assignee

PELTHOS THERAPEUTICS INC.

Inventors

Eric D. LANG, Simon Paul CHANDLER, Deshou JIANG, Richard MALAMUT

Abstract

The present invention relates to pharmaceutical formulations comprising 2-{[3-(5-chloro-2-{2-chloro-5-fluoro-4-[(1,3-thiazol-4-yl)sulfamoyl]phenoxy}phenyl)propyl]amino}acetamide, or a pharmaceutically acceptable salt thereof, for extended release, to methods for preparation thereof, and to uses thereof for treatment of pain or providing peri-operative anesthesia or post-operative analgesia.

CPC Classifications

A61K 31/426 A61K 9/0019 A61K 9/06 A61K 9/08 A61K 9/5031 A61K 47/02 A61K 47/10 A61K 47/14 A61K 47/24 A61K 47/32 A61K 47/38 A61K 47/44 A61P 25/04

Filing Date

2025-10-22

Application No.

19365336

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Last updated

Classification

Agency
USPTO
Published
April 23rd, 2026
Instrument
Rule
Branch
Executive
Legal weight
Binding
Stage
Final
Change scope
Minor

Who this affects

Applies to
Pharmaceutical companies Drug manufacturers Investors
Industry sector
3254 Pharmaceutical Manufacturing
Activity scope
Patent application filing Extended-release formulation Pain treatment
Geographic scope
United States US

Taxonomy

Primary area
Intellectual Property
Operational domain
Legal
Compliance frameworks
GxP
Topics
Pharmaceuticals Public Health

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