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Cyclobenzaprine 5.6mg Daily Transmucosal Fibromyalgia Treatment Patent

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Summary

USPTO published application US20260108477A1, filed December 16, 2025 (Application No. 19421039), discloses methods for treating fibromyalgia using 5.6mg cyclobenzaprine HCl daily via transmucosal administration in a eutectic form with a basifying agent. The application names Seth Lederman and Gregory M. Sullivan as inventors. CPC classifications include A61K 31/135 (quinoline/dihydroquinoline compounds) and A61P 25/00 (nervous system disorders).

“Methods for treating fibromyalgia and one or more of its associated symptoms of pain, sleep disturbance and/or fatigue comprising administering to a subject in need thereof, 5.6 mg cyclobenzaprine HCl per day in one or more dosage units by transmucosal administration, the cyclobenzaprine HCl being in a form of a eutectic, and the one or more dosage units further comprising a basifying agent.”

USPTO , verbatim from source
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About this source

GovPing monitors USPTO Patent Applications - Therapeutics (A61P) for new healthcare & life sciences regulatory changes. Every update since tracking began is archived, classified, and available as free RSS or email alerts — 219 changes logged to date.

What changed

USPTO published application US20260108477A1 disclosing a method of treating fibromyalgia and associated symptoms of pain, sleep disturbance, and fatigue by administering 5.6mg cyclobenzaprine HCl per day via transmucosal route in a eutectic form with a basifying agent.

Affected parties include pharmaceutical developers, drug formulation companies, and researchers studying fibromyalgia treatments; the application may inform R&D strategies for novel drug delivery formulations targeting neurological conditions.

Archived snapshot

Apr 23, 2026

GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.

← USPTO Patent Applications

CYCLOBENZAPRINE TREATMENT FOR FIBROMYALGIA

Application US20260108477A1 Kind: A1 Apr 23, 2026

Inventors

Seth Lederman, Gregory M. Sullivan

Abstract

Methods for treating fibromyalgia and one or more of its associated symptoms of pain, sleep disturbance and/or fatigue comprising administering to a subject in need thereof, 5.6 mg cyclobenzaprine HCl per day in one or more dosage units by transmucosal administration, the cyclobenzaprine HCl being in a form of a eutectic, and the one or more dosage units further comprising a basifying agent.

CPC Classifications

A61K 31/135 A61K 9/006 A61P 25/00

Filing Date

2025-12-16

Application No.

19421039

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Last updated

Classification

Agency
USPTO
Published
April 23rd, 2026
Instrument
Notice
Branch
Executive
Legal weight
Non-binding
Stage
Final
Change scope
Minor

Who this affects

Applies to
Pharmaceutical companies Drug manufacturers Healthcare providers
Industry sector
3254 Pharmaceutical Manufacturing
Activity scope
Patent application Drug formulation Therapeutic research
Geographic scope
United States US

Taxonomy

Primary area
Intellectual Property
Operational domain
Legal
Topics
Pharmaceuticals Public Health

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