NF-κB Inhibitors for Cancer, Inflammatory Diseases
Summary
The USPTO granted Patent US12606528B2 to the University of Pittsburgh covering compounds that inhibit NF-κB activity and their use in treating cancer, inflammatory conditions, and autoimmune diseases. The patent names Beibei Chen, Toren Finkel, and Yuan Liu as inventors and contains 33 claims. The patent application was filed on November 20, 2020.
About this source
GovPing monitors USPTO Patent Grants - Therapeutics (A61P) for new healthcare & life sciences regulatory changes. Every update since tracking began is archived, classified, and available as free RSS or email alerts — 190 changes logged to date.
What changed
The USPTO issued Patent US12606528B2 granting the University of Pittsburgh exclusive rights to NF-κB inhibitor compounds and methods of using them for therapeutic applications. The patent covers pharmaceutical compositions and methods for treating diseases associated with NF-κB activity, including cancer (A61P 35/00), inflammatory conditions (A61P 29/00), and autoimmune diseases (A61P 37/00).
For the assignee University of Pittsburgh, this grant provides enforceable patent rights for commercializing the disclosed compounds. Competitors developing NF-κB inhibitors for similar therapeutic uses should conduct freedom-to-operate analyses to assess potential infringement exposure.
Archived snapshot
Apr 22, 2026GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.
Methods and materials for inhibiting NF-kB activity
Grant US12606528B2 Kind: B2 Apr 21, 2026
Assignee
UNIVERSITY OF PITTSBURGH—OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION
Inventors
Beibei Chen, Toren Finkel, Yuan Liu
Abstract
This document provides compounds that are inhibitors of NF-κB activity, as well as the methods of using such compounds for treating diseases and conditions such as cancer, inflammatory conditions, or autoimmune diseases.
CPC Classifications
A61K 31/421 A61K 31/426 A61K 31/4164 A61P 29/00 A61P 35/00 A61P 37/00
Filing Date
2020-11-20
Application No.
17778492
Claims
33
Mentioned entities
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