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USPTO Grants Patent US12609187B2 for Clinical Budget Data Transformation

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Summary

USPTO granted patent US12609187B2 to Annex IP, LLC on April 21, 2026 for a computer-implemented method of reconciling clinical trial budgets. The system receives procedural items from sponsor budget, Medicare Coverage Analysis, and site charge master sources; normalizes text and generates vector embeddings; constructs approximate nearest-neighbor indices; retrieves candidates by cosine similarity; computes composite match scores combining code equality, textual similarity, numeric price proximity, and billing consistency; selects one-to-one matches via maximum-weight bipartite matching; aligns to Medicare Coverage Analysis items with code-family gating; and writes per-item audit records through an API. The patent contains 20 claims and is classified under CPC G16H 10/20.

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What changed

USPTO has issued patent US12609187B2 to Annex IP, LLC for a data transformation system that reconciles clinical trial budgets by ingesting procedural items from multiple sources, normalizing text, generating vector embeddings, and using cosine similarity with code-dominant composite scoring to match sponsor items to site items via maximum-weight bipartite matching. Unmatched items are flagged and a rule engine resolves cost values and billing categories subject to contract caps. Patent holders and licensees in the clinical trials and health informatics space should be aware of this issued IP covering AI-based budget reconciliation methodology in the G16H classification space. Clinical trial sponsors, contract research organizations, and healthcare technology developers using similar budget-matching approaches may wish to review this patent for freedom-to-operate implications.

The grant does not impose new compliance obligations but represents an expansion of intellectual property rights in the clinical budget technology space. Organizations developing or using clinical trial budget reconciliation systems should evaluate whether their methods fall within the scope of the 20 issued claims.

Archived snapshot

Apr 22, 2026

GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.

← USPTO Patent Grants

Data transformation system for clinical budgets

Grant US12609187B2 Kind: B2 Apr 21, 2026

Assignee

Annex IP, LLC

Inventors

Moe Alsumidaie, Krishma Shah, Jonathan Napitupulu

Abstract

A computer-implemented method for reconciling clinical trial budgets. The method receives procedural items from a sponsor budget source, a Medicare Coverage Analysis source, and a site charge master source; normalizes procedure text; generates unit-length vector embeddings for each item; and constructs an approximate nearest-neighbor index over site embeddings. For each sponsor item the method retrieves candidate site items by cosine similarity and computes a composite match score that combines code equality, textual similarity, numeric price proximity, and billing consistency with code-dominant weighting. One-to-one matches are selected by maximum-weight bipartite matching. Matched pairs are aligned to Medicare Coverage Analysis items with code-family gating, and a rule engine sets a selected cost value and a resolved billing category subject to contract caps. Unmatched items are flagged with candidate explanations. The method writes per-item audit records and returns a machine-readable payload through an application programming interface.

CPC Classifications

G16H 10/20

Filing Date

2025-10-14

Application No.

19357168

Claims

20

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Last updated

Classification

Agency
USPTO
Published
April 21st, 2026
Instrument
Rule
Branch
Executive
Legal weight
Binding
Stage
Final
Change scope
Minor

Who this affects

Applies to
Pharmaceutical companies Drug manufacturers
Industry sector
3254 Pharmaceutical Manufacturing 3254.1 Biotechnology
Activity scope
Patent grant Clinical trial budgeting Health informatics
Geographic scope
United States US

Taxonomy

Primary area
Intellectual Property
Operational domain
Legal
Topics
Healthcare Pharmaceuticals

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