Dipotassium Oxalate for Postoperative Sensitivity in NCCLs (NCT07540299)
ClinicalTrials.gov Studies
Summary
The National Institutes of Health has registered a randomized controlled trial (NCT07540299) on ClinicalTrials.gov evaluating dipotassium oxalate gel as a pre-treatment agent for reducing postoperative sensitivity in non-carious cervical lesion (NCCL) Class V composite restorations. The study will enroll 64 participants randomly assigned to intervention (dipotassium oxalate + adhesive) or control (standard adhesive protocol) groups, with sensitivity assessed via Visual Analog Scale at baseline, 24 hours, 7 days, and 30 days.
What changed
A new clinical trial registration for a randomized controlled study evaluating dipotassium oxalate as a pre-treatment agent for dentin hypersensitivity following Class V composite restorations has been published on ClinicalTrials.gov. The trial will assign 64 participants to receive either dipotassium oxalate gel prior to adhesive application or standard adhesive protocol without pretreatment.
This registration is informational only and does not impose compliance obligations. Clinical investigators and dental healthcare providers conducting similar research may wish to note the study parameters as potential comparable research or to identify gaps in current treatment protocols for postoperative sensitivity in NCCL restorations.
Archived snapshot
Apr 21, 2026GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.
Dipotassium Oxalate for Postoperative Sensitivity in NCCLs
N/A NCT07540299 Kind: NA Apr 20, 2026
Abstract
Postoperative sensitivity is a common complication following Class V composite restorations, particularly in non-carious cervical lesions (NCCLs). This randomized controlled trial aims to evaluate the effectiveness of dipotassium oxalate as a pre-treatment agent in reducing postoperative sensitivity.
A total of 64 participants will be randomly assigned into two groups: an intervention group receiving dipotassium oxalate prior to adhesive application, and a control group receiving standard adhesive protocol without pretreatment. Sensitivity will be assessed using a Visual Analog Scale (VAS) in response to cold and air stimuli at baseline, 24 hours, 7 days, and 30 days.
The study aims to determine whether dipotassium oxalate significantly reduces postoperative sensitivity and can be incorporated into routine restorative dental practice.
Conditions: Dentin Hypersensitivity, Post Operative Sensitivity Control
Interventions: Dipotassium Oxalate Gel
Mentioned entities
Related changes
Get daily alerts for ClinicalTrials.gov Studies
Daily digest delivered to your inbox.
Free. Unsubscribe anytime.
Source
About this page
Every important government, regulator, and court update from around the world. One place. Real-time. Free. Our mission
Source document text, dates, docket IDs, and authority are extracted directly from NIH.
The summary, classification, recommended actions, deadlines, and penalty information are AI-generated from the original text and may contain errors. Always verify against the source document.
Classification
Who this affects
Taxonomy
Browse Categories
Get alerts for this source
We'll email you when ClinicalTrials.gov Studies publishes new changes.
Subscribed!
Optional. Filters your digest to exactly the updates that matter to you.