Changeflow GovPing Healthcare & Life Sciences Muscarinic Receptor Allosteric Modulators, Univ...
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Muscarinic Receptor Allosteric Modulators, University of Toledo, 23rd Apr

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Summary

The University of Toledo has published patent application US20260109674A1 covering allosteric modulators of muscarinic receptors and methods of making and using the same, filed on October 23, 2023. The application names six inventors: William S. Messer Jr., Hazel Cunningham, Corey Widman, John Ellis, Isaac Schiefer, and Gina Kaup. This publication makes the technical disclosure publicly available, establishing priority date without granting enforceable rights until and unless the application issues as a granted patent.

“Allosteric modulators of muscarinic receptors, and methods of making and using the same, are described.”

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About this source

GovPing monitors USPTO Patent Applications - Therapeutics (A61P) for new healthcare & life sciences regulatory changes. Every update since tracking began is archived, classified, and available as free RSS or email alerts — 223 changes logged to date.

What changed

The University of Toledo has published patent application US20260109674A1 titled 'Allosteric Modulation of Muscarinic Acetylcholine Receptor Efficacy,' covering allosteric modulators of muscarinic receptors and methods of making and using the same. The application was filed on October 23, 2023 and lists six inventors: William S. Messer Jr., Hazel Cunningham, Corey Widman, John Ellis, Isaac Schiefer, and Gina Kaup.

For pharmaceutical and biotechnology companies, this publication establishes a public record of the University of Toledo's claimed subject matter. Competitors developing allosteric modulators of muscarinic receptors should review this publication for potential freedom-to-operate concerns and assess whether their own R&D programs may overlap with the disclosed claims. This is a published application, not a granted patent — enforceable rights will only arise upon issuance of a granted patent following examination.

Archived snapshot

Apr 24, 2026

GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.

← USPTO Patent Applications

ALLOSTERIC MODULATION OF MUSCARINIC ACETYLCHOLINE RECEPTOR EFFICACY

Application US20260109674A1 Kind: A1 Apr 23, 2026

Assignee

The University of Toledo

Inventors

William S. Messer, JR., Hazel Cunningham, Corey Widman, John Ellis, Isaac Schiefer, Gina Kaup

Abstract

Allosteric modulators of muscarinic receptors, and methods of making and using the same, are described.

CPC Classifications

C07D 215/56 A61K 31/343 A61K 31/403 A61K 31/47 A61P 25/14 C07D 209/38 C07D 307/80

Filing Date

2023-10-23

Application No.

19117060

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Last updated

Classification

Agency
USPTO
Published
April 23rd, 2026
Instrument
Notice
Branch
Executive
Legal weight
Non-binding
Stage
Final
Change scope
Minor

Who this affects

Applies to
Pharmaceutical companies Legal professionals Manufacturers
Industry sector
3254.1 Biotechnology
Activity scope
Patent filing IP licensing research
Geographic scope
United States US

Taxonomy

Primary area
Intellectual Property
Operational domain
Legal
Topics
Pharmaceuticals Biotechnology

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