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Tsinghua University Mirror Nucleic Acid Replication Patent

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Summary

The USPTO granted Patent No. US12606808B2 to Tsinghua University for a method of replicating mirror nucleic acids. The patent covers reacting a mirror nucleic acid template, a mirror nucleic acid primer, and mirror dNTPs/rNTPs in the presence of a mirror nucleic acid polymerase. The patent contains 12 claims and was filed on May 31, 2022.

Published by USPTO on changeflow.com . Detected, standardized, and enriched by GovPing. Review our methodology and editorial standards .

What changed

The USPTO issued Patent No. US12606808B2 to Tsinghua University for a mirror nucleic acid replication method. The patent claims cover a process using a mirror nucleic acid template, mirror nucleic acid primer, mirror dNTPs/rNTPs, and a mirror nucleic acid polymerase to obtain a mirror nucleic acid. The grant finalises 12 claims under CPC classifications including C12N 9/1252, C12N 9/127, and C12P 19/34.

Tsinghua University now holds enforceable intellectual property rights over this mirror nucleic acid replication technology. Third parties seeking to use or commercialise mirror nucleic acid replication methods consistent with the claimed scope should evaluate potential licensing needs or design-around options.

Archived snapshot

Apr 21, 2026

GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.

← USPTO Patent Grants

Mirror nucleic acid replication system

Grant US12606808B2 Kind: B2 Apr 21, 2026

Assignee

Tsinghua University

Inventors

Ting Zhu, Lei Liu, Weiliang Xu, Zimou Wang, Wenjun Jiang, Jiaxing Wang, Linping Yu

Abstract

Provided is a method for replicating a mirror nucleic acid, comprising: reacting a mirror nucleic acid template, a mirror nucleic acid primer and mirror dNTPs/rNTPs in the presence of a mirror nucleic acid polymerase, so as to obtain the mirror nucleic acid.

CPC Classifications

C12N 9/1252 C12N 9/127 C12N 15/10 C12N 15/1068 C12P 19/34 C12Y 207/07007 C12Y 207/07048

Filing Date

2022-05-31

Application No.

17828083

Claims

12

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Last updated

Classification

Agency
USPTO
Published
April 21st, 2026
Instrument
Rule
Branch
Executive
Legal weight
Binding
Stage
Final
Change scope
Minor
Document ID
US12606808B2

Who this affects

Applies to
Educational institutions
Industry sector
3254.1 Biotechnology
Activity scope
Patent grant Biotech research
Geographic scope
United States US

Taxonomy

Primary area
Intellectual Property
Operational domain
Legal
Topics
Pharmaceuticals

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