INFEX Therapeutics Pyrrole Acid Synthesis Patent Grant
Summary
The USPTO granted patent US12606524B2 to INFEX Therapeutics Limited for a novel method of synthesizing pyrrole acid derivatives that function as metallo-β-lactamase inhibitors. These compounds are designed for use in combination with carbapenem antibacterial agents to treat bacterial infections. The patent claims priority to application 18246777, filed October 6, 2021, and contains 3 claims under CPC classification C07D 207/48.
What changed
The USPTO issued patent US12606524B2 to INFEX Therapeutics Limited covering novel synthetic methods for pyrrole acid derivatives. The compounds are enzyme inhibitors specifically classified as metallo-β-lactamase inhibitors intended for combination therapy with carbapenem antibacterial agents. The patent was granted with 3 claims under the organic chemistry classification C07D 207/48.
Pharmaceutical companies developing carbapenem-based antibiotic regimens or researching β-lactamase inhibitor combinations should review this patent when assessing freedom-to-operate for related synthesis methods. Biotechnology firms in the anti-infectives space may find licensing opportunities with INFEX Therapeutics relevant to their product pipelines.
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Apr 21, 2026GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.
Synthesis of pyrrole acid derivatives
Grant US12606524B2 Kind: B2 Apr 21, 2026
Assignee
INFEX Therapeutics Limited
Inventors
Andrew Wilkinson, Ian Cooper, David Orr, Jonathan Finlayson, Adam Bunt, James Kirkham, David Lyth, Kevin Blades
Abstract
This invention relates to the synthesis of compounds that can be used to treat bacterial infections in combination with other antibacterial agents, and more specifically in combination with a class of antibacterial agents known as carbapenems. The compounds resulting from the novel methods of the present invention are enzyme inhibitors and more particularly are metallo-β-lactamase inhibitors.
CPC Classifications
C07D 207/48
Filing Date
2021-10-06
Application No.
18246777
Claims
3
Parties
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