CT Image-Assisted Colonoscopy Improves Insertion Time, Patient Comfort
Summary
The NIH ClinicalTrials.gov registry has posted a new single-blind randomized controlled trial (NCT07541924) evaluating whether pre-existing CT abdominal/pelvic imaging can improve colonoscopy outcomes. The study will compare image-assisted colonoscope insertion against standard colonoscopy, measuring cecal intubation time, patient comfort, physician workload, and examination quality. Estimated enrollment and study completion dates are listed on the registry.
“This single-blind, randomized controlled trial evaluates whether image-assisted colonoscope insertion, based on pre-existing abdominal/pelvic CT scans, can improve cecal intubation time, enhance patient experience, reduce operator workload, and improve overall examination quality compared with standard colonoscopy.”
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What changed
This registry entry adds a new clinical trial (NCT07541924) to the ClinicalTrials.gov database. The trial evaluates CT-based image-assisted colonoscopy insertion against standard colonoscopy in a single-blind randomized controlled trial. Participating sites will enroll patients undergoing colonoscopy and measure outcomes including cecal intubation time, patient experience, and operator workload.
Healthcare institutions and clinical investigators conducting or considering similar procedural improvement studies should note this prospective randomized evidence will add to the limited body of prospective data on pre-procedure CT colonography utility for colonoscopy guidance. Sites with existing abdominal/pelvic CT access may find the trial protocol relevant to their quality-improvement programs.
Archived snapshot
Apr 22, 2026GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.
The Impact of Image-Assisted Colonoscope on Patient Experience, Physician Workload, and Examination Quality
N/A NCT07541924 Kind: NA Apr 21, 2026
Abstract
Colonoscopy is the cornerstone for colorectal cancer screening, diagnosis, and post-treatment surveillance. Procedural quality is influenced by patient anatomy, particularly variations in colonic configuration such as sigmoid redundancy, looping, and low-lying transverse colon. These features prolong insertion time, increase patient discomfort, and elevate physician workload.
Evidence suggests that prior CT imaging can provide objective and individualized information on colonic anatomy-such as redundancy, angulation, and tortuosity-potentially predicting procedural difficulty. However, existing studies are mainly retrospective or descriptive, lacking prospective randomized evidence on clinical utility.
This single-blind, randomized controlled trial evaluates whether image-assisted colonoscope insertion, based on pre-existing abdominal/pelvic CT scans, can improve cecal intubation time, enhance patient experience, reduce operator workload, and improve overall examination quality compared with standard colonoscopy.
Conditions: Colorectal Cancer Screening, Colonic Polyps/Colonoscopy/Colorectal Neoplasms, Difficult Colonoscopy, Colonoscopy-Related Discomfort
Interventions: CT-Based Image-Assisted Colonoscope Insertion
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