Clinical Outcomes After Non-curative Endoscopic Resection in Early Colorectal Cancer
Summary
The NIH has registered a new observational study (NCT07542171) on ClinicalTrials.gov to evaluate clinical outcomes in patients with early colorectal cancer who undergo non-curative endoscopic resection. The multicenter study will compare recurrence and survival outcomes between different management strategies, including additional surgery or surveillance, and will develop a risk stratification model to guide individualized treatment decisions.
What changed
A new observational study (NCT07542171) has been registered on ClinicalTrials.gov by NIH. The study will enroll patients with non-curative resection following endoscopic treatment across multiple centers and compare recurrence and survival outcomes between different management strategies, including additional surgery or surveillance. Baseline demographic, endoscopic, and pathological characteristics will be systematically collected under real-world clinical decisions.
Healthcare providers and clinical researchers involved in colorectal cancer management may benefit from monitoring this study's outcomes. The research is expected to provide real-world evidence to refine risk assessment, reduce unnecessary surgery, and improve personalized management for patients with early colorectal cancer after non-curative endoscopic resection.
Archived snapshot
Apr 22, 2026GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.
Clinical Outcomes After Non-curative Endoscopic Resection in Early Colorectal Cancer: A Multicenter Study
Observational NCT07542171 Kind: OBSERVATIONAL Apr 21, 2026
Abstract
This multicenter study aims to evaluate clinical outcomes and optimize management strategies in patients with early colorectal cancer who undergo non-curative endoscopic resection.
Patients with non-curative resection following endoscopic treatment will be enrolled across multiple centers and managed according to real-world clinical decisions, including additional surgery or surveillance. Baseline demographic, endoscopic, and pathological characteristics will be systematically collected.
The primary objective is to compare recurrence and survival outcomes between different management strategies. Secondary objectives include identifying prognostic factors associated with recurrence and developing a risk stratification model to guide individualized treatment decisions.
All participants will undergo standardized follow-up according to clinical guidelines. This study is expected to provide real-world evidence to refine risk assessment, reduce unnecessary surgery, and improve personalized management for patients with early colorectal cancer after non-curative endoscopic resection.
Conditions: Early Colorectal Cancer, Non-curative Endoscopic Resection
Interventions: Additional Surgery, Surveillance
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