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Missouri AG Expands Kratom Investigation to Target Supply Chain

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Summary

Missouri AG expands Kratom investigation, adds 10 entities

What changed

Missouri Attorney General Catherine Hanaway expanded the state's investigation into unapproved, unsafe opioid products to include 10 additional entities across the supply chain—4 manufacturers, 3 distributors, and 3 retailers—bringing the total number of entities under investigation to 22. The AG's office issued Civil Investigative Demands (CIDs) seeking information on manufacturing, labeling, marketing, ingredients, testing, adverse events, supply sources, and alkaloid concentration.\n\nManufacturers, distributors, and retailers of 7-hydroxymitragynine (7-OH) products face immediate compliance obligations. Retailers are urged to remove dangerous products from shelves immediately. The AG's office has already filed suit against CBD American Shaman and related entities, signaling aggressive enforcement. The CDC reported a 1,200% increase in annual hospitalizations from 7-OH exposure from 2015 to 2025, and these products have resulted in deaths of Missouri residents.

What to do next

  1. Retailers must immediately remove dangerous 7-OH/kratom alkaloid products from shelves
  2. Manufacturers and distributors receiving Civil Investigative Demands must preserve records and respond within statutory deadlines
  3. Companies in the supply chain should review labeling, marketing, and testing practices for compliance with Missouri law

Penalties

Civil Investigative Demands are enforceable by court order; the AG has filed suit against CBD American Shaman and related entities for manufacture and sale of unapproved opioid products

Archived snapshot

Apr 8, 2026

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Catherine L. Hanaway
Missouri Attorney General

Explore Section

Catherine L. Hanaway
Missouri Attorney General

Attorney General Hanaway Expands Kratom Investigation to Target Supply Chain

Home 9 Press Release 9 Attorney General Hanaway Expands Kratom Investigation to Target Supply Chain JEFFERSON CITY, Mo. – **** Today, Missouri Attorney General Catherine Hanaway announced that her office is expanding its statewide investigation into kratom and 7-hydroxymitragynine (7-OH) products to include 10 additional entities across the supply chain including manufacturers, distributors, and retailers. This action brings the total number of entities under investigation to 22.

“Businesses owners who choose to manufacture, distribute, or sell unapproved, unsafe, opioid products in Missouri will be held to account,” said Attorney General Hanaway. “Our message to retailers: remove dangerous kratom alkaloid products from shelves immediately. We will continue to uncover the facts and root out bad actors at every level of the supply chain.”

The Attorney General’s Office is taking a holistic approach to investigating the kratom supply network, sending additional Civil Investigative Demands (CIDs) as authorized by statute to businesses believed to be manufacturing, selling, or distributing kratom products that may violate Missouri law. The Attorney General’s ongoing investigation seeks information regarding manufacturing, labeling, marketing, ingredients, testing, adverse events, supply sources, and alkaloid concentration.

The 10 CIDs being served can be read here:

Manufacturers:

Distributors:

Retailers:

Because kratom products are not regulated like other drugs, potency and purity vary widely, and many products contain dangerous levels of 7-OH far exceeding what occurs naturally in the plant. 7-OH is extracted and consumed in concentrated forms that are addictive, dangerous, and function like opiates. In March, the CDC published data showing that annual hospitalizations from kratom exposure increased by 1,200 percent from 2015 to 2025. These products have resulted in the deaths of Missouri residents, and Missouri’s Department of Health and Senior Services has warned Missourians against using 7-OH.

As a result of the office’s earlier investigative efforts, the Attorney General filed suit against CBD American Shaman and related entities for the manufacture, distribution, and retail sale of kratom and its alkaloids on March 31, 2026.

The latest tranche of CIDs requires each recipient to disclose, among other things, detailed information about how their products are manufactured, labeled, and marketed; all ingredients used; any representations regarding safety, health effects, or “safe” dosage levels; communications with consumers about adverse effects; and any materials showing whether the company sold unapproved drugs in violation of federal or state law. The CIDs also seek information to determine whether these businesses failed to disclose the presence of psychoactive substances such as 7-OH to Missouri consumers.

Missourians who believe they were misled or harmed by kratom products are encouraged to file a complaint online at ago.mo.gov or call the Consumer Protection hotline at 800-392-8222.

The press release announcing the initial investigation expansion into kratom manufacturers and retailers from December 2025 can be read here.

The press release announcing the Attorney General’s lawsuit against CBD American Shaman can be read here.

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Last updated

Classification

Agency
Missouri AG
Instrument
Enforcement
Legal weight
Binding
Stage
Final
Change scope
Substantive

Who this affects

Applies to
Manufacturers Retailers Importers and exporters
Industry sector
3254 Pharmaceutical Manufacturing 4231 Wholesale Trade 4411 Retail Trade
Activity scope
Product safety investigation CID issuance Opioid-like substance enforcement
Geographic scope
US-MO US-MO

Taxonomy

Primary area
Product Safety
Operational domain
Compliance
Topics
Consumer Protection Pharmaceuticals Public Health

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