America First Global Health Strategy MOU with Cambodia
Summary
The U.S. Department of State signed a bilateral health cooperation MOU with Cambodia under the America First Global Health Strategy. The $36.1 million five-year agreement provides over $30.8 million in U.S. funding alongside $5.3 million in Cambodian commitments to strengthen infectious disease prevention and response capabilities targeting HIV/AIDS, malaria, and tuberculosis.
What changed
On April 2, 2026, the United States and Royal Government of Cambodia signed a bilateral health MOU under the Trump Administration's America First Global Health Strategy (AFGHS). The $36.1 million agreement includes over $30.8 million in U.S. assistance and more than $5.3 million in Cambodian domestic expenditures, with $5 million dedicated to global health security for laboratory networks and malaria elimination efforts. This is the first AFGHS MOU signed in Asia and the 28th globally, representing more than $20.5 billion in new health funding across all partner countries.
This MOU creates no immediate compliance obligations for private entities. U.S. government stakeholders and Cambodian counterparts should coordinate on implementation milestones and reporting requirements under the five-year framework. The agreement preserves and transitions decades of U.S. global health investments to locally led Cambodian leadership over its national health system.
Archived snapshot
Apr 7, 2026GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.
Home Office of the Spokesperson Press Releases … Charting a New Phase of Trump Administration’s America First Global Health Strategy in Asia, Beginning with Cambodia hide
Charting a New Phase of Trump Administration’s America First Global Health Strategy in Asia, Beginning with Cambodia
Press Statement
Thomas "Tommy" Pigott, Principal Deputy Spokesperson
April 6, 2026
On April 2, the United States signed a bilateral health cooperation Memorandum of Understanding (MOU) with the Royal Government of Cambodia through the Trump Administration’s America First Global Health Strategy (AFGHS). This landmark five-year MOU is the first to be signed through the Trump Administration’s AFGHS in Asia, and advances shared global health goals, such as preventing the spread of infectious diseases like HIV/AIDS, malaria, and tuberculosis.
Working with Congress, the Department of State intends to provide more than $30.8 million to strengthen and sustain Cambodian infectious disease prevention and response capabilities and accurately identify pathogens of epidemic and pandemic potential before they spread internationally. Through the bilateral health MOU, the Royal Government of Cambodia has committed to increasing its own domestic expenditures by more than $5.3 million, assuming greater ownership of their commodity chains while continuing to rollout new innovative diagnostics, vaccines, drugs, and other life-saving interventions.
The jointly decided $36.1 million bilateral health MOU also includes $5 million in global health security funding to bolster and sustain a robust network of laboratories and aims to achieve malaria elimination in Cambodia, ultimately strengthening independent, locally led Cambodian leadership over its national health system. Through the Trump Administration’s AFGHS, this bilateral MOU ensures that decades of cooperation and gains made in Cambodia through U.S. global health support are preserved and owned by the Cambodian government.
America First Global Health Strategy Memoranda of Understanding (MOUs) signed so far represent more than $20.5 billion in new health funding including more than $12.7 billion in U.S. assistance alongside $7.8 billion in co-investment from recipient countries, building on decades of progress fighting HIV/AIDS, malaria, tuberculosis, and other infectious diseases around the world. As of April 2, the State Department has signed 28 bilateral global health MOUs with Angola, Botswana, Burkina Faso, Burundi, Cambodia, Cameroon, Côte d’Ivoire, the Democratic Republic of the Congo, the Dominican Republic, El Salvador, Eswatini, Ethiopia, Guatemala, Guinea, Honduras, Kenya, Lesotho, Liberia, Madagascar, Malawi, Mozambique, Niger, Nigeria, Panama, Rwanda, Senegal, Sierra Leone, and Uganda.
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Bureau of East Asian and Pacific Affairs Bureau of Global Health Security and Diplomacy Cambodia Health Security Office of the Spokesperson
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