PRISM Regulatory Modernization Cooperative Agreement

Pathways for Regulatory Innovation and Strategic Modernization (PRISM)

Agency: Food and Drug Administration

Assistance Listings: 93.103 -- Food and Drug Administration Research

Last Updated: March 31, 2026 View version history on Grants.gov

Description

The Pathways for Regulatory Innovation and Strategic Modernization (PRISM) cooperative agreement is intended to advance public health by strengthening the scientific, collaborative, and operational foundations needed to modernize regulatory oversight in an increasingly complex and rapidly evolving public health landscape. As innovation in medical products, diagnostics, foods, and digital health accelerates, our nation must continuously adapt its regulatory science approaches to ensure timely access to safe, effective, and high-quality products for the American public. PRISM is designed to support this modernization by enabling forward-looking, non-regulatory collaborations that align with the Commissioner’s strategic priorities and the Administration’s broader public health goals.

PRISM provides a flexible, scalable approach to patient, consumer, industry, academia, and healthcare workforce engagement to generate applied scientific knowledge, tools, and approaches that enhance regulatory predictability, efficiency, and transparency. By leveraging independent expertise and real-world insights, PRISM bridges gaps between innovation and regulation to optimize uptake of emerging technologies, evolving consumer needs, and new sources of evidence such as real-world data and real-world evidence.

Eligibility

Eligible applicants

Miscellaneous

• Other

Additional information

Only the following applicant is eligible to apply for this single source funding: Reagan-Udall Foundation for the Food and Drug Administration.

Grantor contact information

Description

Patrick Johnson
Grants Management Specialist

Email

Contact Patrick

patrick.johnson@fda.hhs.gov

Documents

Download all
| File name | Description | Last updated |
| --- | --- | --- |
| RFA-FD-26-007PathwaysforRegulatoryInnovationandStrategicModernization.pdf | Notice of Funding Opportunity Announcement (NOFO) | Mar 31, 2026 07:07 PM UTC |

Link to additional information

--

Closing: April 30, 2026

Application process

This site is a work in progress. Go to www.grants.gov to apply, track application status, and subscribe to updates. View on Grants.gov

Award

$1,300,000

Program Funding

1

Expected awards

$--

Award Minimum

$1,300,000

Award Maximum

Funding opportunity number:

RFA-FD-26-007

Cost sharing or matching requirement:

No Funding instrument type:

Cooperative agreement

Opportunity Category:

Discretionary

Opportunity Category Explanation:

-- Category of Funding Activity:

Agriculture

Consumer protection

Food and nutrition

Health

Category Explanation:

--

History

Version:

2

Posted date:

March 31, 2026

Archive date:

May 30, 2026