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Trial Comparing Ultrasound-guided vs Arthroscopic Guided PRF Injection for TMJ Disc Displacement

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Summary

NIH registered a clinical trial (NCT07535073) comparing ultrasound-guided versus arthroscopic guided platelet rich fibrin injection for temporomandibular joint disc displacement. The trial will evaluate pain reduction, improvement of mandibular function, and patient-reported outcomes. No regulatory obligations or compliance requirements are created by this study registration.

Published by NIH on changeflow.com . Detected, standardized, and enriched by GovPing. Review our methodology and editorial standards .

What changed

NIH registered a new clinical trial on ClinicalTrials.gov comparing two methods of delivering platelet rich fibrin injections for temporomandibular joint disc displacement. The trial will assess pain reduction, mandibular function improvement, and patient-reported outcomes between ultrasound-guided and arthroscopic guided approaches. This is an informational study registration that does not create regulatory obligations.

Healthcare providers and clinical investigators conducting related research may find this trial relevant for understanding current comparative effectiveness studies in the TMJ treatment space. The registration provides public visibility into ongoing clinical research but does not impose any compliance or reporting requirements.

Archived snapshot

Apr 16, 2026

GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.

← ClinicalTrials.gov Studies

Ultrasound-guided Versus Arthroscopic Guided PRF Injection for TMJ Disc Displacement.

N/A NCT07535073 Kind: NA Apr 16, 2026

Abstract

To compare the clinical effectiveness of ultrasound-guided versus arthroscopic guided platelet rich fibrin injection in the management of anterior disc displacement with reduction of the temporomandibular joint, in terms of pain reduction, improvement of mandibular function, and patient-reported outcomes.

Conditions: TMJ Disc Displacement With Reduction

Interventions: ultrasound guided platelet rich fibrin injection, Arthroscopic guided platelet rich Fibrin injection

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Last updated

Classification

Agency
NIH
Instrument
Notice
Legal weight
Non-binding
Stage
Final
Change scope
Minor
Document ID
NCT07535073

Who this affects

Applies to
Healthcare providers Clinical investigators
Industry sector
6211 Healthcare Providers
Activity scope
Clinical trial registration Medical research
Geographic scope
United States US

Taxonomy

Primary area
Healthcare
Operational domain
Clinical Operations
Topics
Pharmaceuticals Medical Devices

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