Montelukast Phase 2 Trial for Acute Myocardial Infarction
Summary
NIH registered a Phase 2 randomized controlled trial (NCT07537868) evaluating Montelukast 10 mg oral tablets for acute myocardial infarction. The trial, sponsored by Mansoura University (Egypt), will enroll participants randomized to Montelukast or placebo to assess anti-inflammatory and cardioprotective effects via inflammatory markers and cardiac injury indicators. The study has an estimated start date of April 17, 2026.
What changed
This notice registers a new Phase 2 clinical trial on ClinicalTrials.gov (NCT07537868) to evaluate Montelukast in acute myocardial infarction patients. The randomized, placebo-controlled study will assess whether Montelukast 10 mg influences inflammatory markers and reduces cardiac injury following heart attack.
Affected parties including trial sponsors, clinical investigators, and pharmaceutical companies should note this trial registration for competitive landscape awareness and patient referral considerations. The trial does not create compliance obligations for third parties; it is an informational record of an ongoing research study.
Archived snapshot
Apr 17, 2026GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.
Effect of Montelukast on Inflammatory Markers and Cardiac Injury in Patients With Acute Myocardial Infarction
Phase 2 NCT07537868 Kind: PHASE2 Apr 17, 2026
Abstract
This is a randomized controlled clinical trial designed to evaluate the therapeutic effects of Montelukast in patients diagnosed with Acute Myocardial Infarction (AMI). The study aims to investigate whether the administration of Montelukast influences inflammatory markers and the extent of cardiac injury following a heart attack.Participants will be randomly assigned to receive either the active medication or a placebo to provide high-quality evidence regarding the drug's potential cardioprotective and anti-inflammatory properties. The trial is conducted through the Faculty of Pharmacy and Faculty of Medicine at Mansoura University
Conditions: Acute Myocardial Infarction (AMI)
Interventions: Montelukast 10 Mg Oral Tablet, placebo
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