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Mirror Therapy for Complex Regional Pain Syndrome in Post-Stroke Patients

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Summary

The NIH ClinicalTrials.gov registry has registered a clinical trial (NCT07537465) evaluating mirror therapy for complex regional pain syndrome in post-stroke patients. The randomized controlled trial will compare mirror therapy to sham mirror therapy over 4 weeks. Participants will receive conventional rehabilitation therapy and be assessed using clinical scales, electrophysiological tests, and ultrasonographic measurements.

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What changed

A new clinical trial evaluating mirror therapy effectiveness for complex regional pain syndrome in post-stroke patients has been registered on ClinicalTrials.gov. The trial will enroll participants randomly assigned to mirror therapy or sham mirror therapy groups receiving 20 minutes of daily treatment for 4 weeks alongside conventional rehabilitation and contrast bath therapy.

Healthcare providers and clinical investigators conducting stroke rehabilitation research should note this trial for awareness. The study may inform future evidence-based practices for managing CRPS in post-stroke patients, though this registry entry creates no compliance obligations.

Archived snapshot

Apr 17, 2026

GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.

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Mirror Therapy for Complex Regional Pain Syndrome in Stroke Patients

N/A NCT07537465 Kind: NA Apr 17, 2026

Abstract

The goal of this clinical study is to evaluate the effectiveness of mirror therapy in treating complex regional pain syndrome (CRPS) in patients after stroke using clinical assessments, electrophysiological evaluations, and ultrasonographic measurements by comparing pre- and post-treatment outcomes.

The main questions it aims to answer are:

Does mirror therapy lead to improvements in clinical outcomes in post-stroke patients with CRPS when assessed before and after treatment? Does mirror therapy reduce pain, improve motor function, and enhance functional independence based on clinical assessments? Does mirror therapy reduce swelling (edema) in the affected limb as measured by ultrasonographic evaluations? Does mirror therapy lead to changes in sympathetic nervous system function as assessed by electrophysiological evaluations?

Researchers will compare mirror therapy to sham mirror therapy (a similar procedure without therapeutic effect) to determine its effectiveness.

Participants will:

Be randomly assigned to either a mirror therapy group or a control group Receive conventional rehabilitation therapy and contrast bath treatment for 4 weeks Receive either mirror therapy or sham mirror therapy for 20 minutes daily Be evaluated before and after treatment using clinical scales, electrophysiological tests, and ultrasonographic measurements.

Conditions: Stroke, Complex Regional Pain Syndrome I (CRPS I), Mirror Therapy

Interventions: Mirror Therapy, Sham Mirror Therapy

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Last updated

Classification

Agency
NIH
Published
April 17th, 2026
Instrument
Notice
Legal weight
Non-binding
Stage
Final
Change scope
Minor
Document ID
NCT07537465

Who this affects

Applies to
Healthcare providers Clinical investigators
Industry sector
6211 Healthcare Providers
Activity scope
Clinical trial registration Medical device research
Geographic scope
United States US

Taxonomy

Primary area
Healthcare
Operational domain
Clinical Operations
Topics
Clinical Operations

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