Internet-Based CBT for Anxiety and Depression, Singapore, NCT07532551
Summary
NIH's ClinicalTrials.gov has registered a clinical trial (NCT07532551) in Singapore evaluating Internet-based Cognitive Behavioural Therapy (iCBT) for adults with mild-to-moderate anxiety and/or depression. The randomized controlled trial will compare guided iCBT to usual care (traditional CBT) to assess clinical effectiveness, cost-effectiveness, and acceptability. Participants will receive structured digital modules with therapist support. The trial is expected to complete in April 2026.
What changed
This document registers a new clinical trial on ClinicalTrials.gov. The trial will evaluate whether Internet-based Cognitive Behavioural Therapy (iCBT) effectively reduces symptoms of anxiety and depression compared to traditional CBT. Researchers will also assess cost-effectiveness and factors influencing user adoption and engagement among Singaporeans in primary and community healthcare settings.
Healthcare providers and clinical investigators involved in mental health treatment in Singapore should be aware of this trial, which may inform future iCBT implementation in the region. Patients seeking digital mental health interventions may benefit from understanding this comparative effectiveness research. The study addresses accessibility and cost considerations for delivering CBT through digital platforms.
Archived snapshot
Apr 16, 2026GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.
Internet-Based Cognitive Behavioural Therapy (iCBT) for Anxiety and Depression in Singapore
N/A NCT07532551 Kind: NA Apr 16, 2026
Abstract
Cognitive-behavioural therapy (CBT) has a robust evidence base for treating anxiety disorders and depression, including transdiagnostic CBT. Internet-based CBT (iCBT) offers a new approach to delivering these therapies. iCBT is a digital adaptation of traditional CBT that leverages digital platforms to deliver similar therapeutic interventions. iCBT encompasses structured programmes that provide users with tools and techniques to manage mental health issues such as depression and anxiety. The digital format ensures timely access to CBT and typically includes interactive modules, videos, self-assessment tools, and virtual therapist support. This study aims to evaluate the effectiveness of iCBT in reducing symptoms of anxiety and depression, as well as its cost-effectiveness and acceptability in local context.
The main questions it aims to answer are:
- Do participants receiving iCBT show a reduction in symptoms of anxiety and/or depression, and does the effectiveness of iCBT vary based on individual user characteristics?
- What are the factors that influence the acceptance, adoption, and engagement rates of iCBT among Singaporeans?
- Is iCBT more cost-effective as compared to usual care?
Researchers will compare guided iCBT to usual care (traditional CBT) to assess iCBT's clinical effectiveness, cost-effectiveness, and acceptability in Singapore's primary and community healthcare settings.
Participants in the intervention group will:
- Undergo guided iCBT intervent...
Conditions: Depression and/or Anxiety in the Mild-to-moderate Range, Cognitive Behavioral Therapy
Interventions: Internet-delivered cognitive behavioural therapy (iCBT)
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