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Guselkumab High-Dose vs Standard-Dose Study in Chinese Moderate-to-Severe Plaque Psoriasis

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Summary

NIH registered a clinical trial (NCT07532486) on ClinicalTrials.gov evaluating the efficacy, safety, tolerability, and drug survival of guselkumab at high-dose and extended-interval regimens versus standard-dose in Chinese participants with moderate-to-severe plaque psoriasis. The interventional study compares two guselkumab dosing approaches. This is an administrative registration entry with no regulatory compliance obligations.

Published by NIH on changeflow.com . Detected, standardized, and enriched by GovPing. Review our methodology and editorial standards .

What changed

NIH added a new clinical trial registration for a Phase 4 interventional study comparing high-dose and extended-interval guselkumab dosing against standard dosing in Chinese adults with moderate-to-severe plaque psoriasis. The study will assess efficacy, safety, tolerability, and drug survival over the study period.

Healthcare providers and pharmaceutical companies conducting clinical research in China should note this trial for competitive intelligence and potential collaboration opportunities. The study's findings may inform future dosing recommendations for guselkumab in Asian populations, though this registration itself creates no compliance obligations.

Archived snapshot

Apr 16, 2026

GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.

← ClinicalTrials.gov Studies

A Study to Evaluate Comparative Efficacy and Safety of Guselkumab in High-dose and Extended-interval Versus Standard-dose in Chinese Participants of Moderate-to-severe Plaque Psoriasis

N/A NCT07532486 Kind: NA Apr 16, 2026

Abstract

The purpose of this study is to evaluate the efficacy, safety, tolerability and drug survival of guselkumab in high-dose and extended-interval versus standard-dose in Chinese participants with moderate to severe plaque psoriasis.

Conditions: Psoriasis

Interventions: Guselkumab, Guselkumab

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Last updated

Classification

Agency
NIH
Published
April 16th, 2026
Instrument
Notice
Legal weight
Non-binding
Stage
Final
Change scope
Minor
Document ID
NCT07532486

Who this affects

Applies to
Pharmaceutical companies
Industry sector
3254 Pharmaceutical Manufacturing
Activity scope
Clinical research Drug trials
Geographic scope
United States US

Taxonomy

Primary area
Pharmaceuticals
Operational domain
Clinical Operations
Compliance frameworks
GxP
Topics
Healthcare Public Health

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