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Decision Aid Efficacy in Low Risk Thyroid Cancer

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Summary

NIH ClinicalTrials.gov registered a clinical trial (NCT07536412) evaluating whether a decision aid pamphlet reduces decision anxiety and improves treatment decision readiness in low-risk thyroid cancer patients. The study will enroll patients diagnosed with differentiated thyroid cancer, papillary thyroid microcarcinoma, or papillary thyroid carcinoma to receive the decision aid before meeting with a surgeon. The intervention provides information about three treatment options (total thyroidectomy, partial thyroidectomy, or active surveillance) and questions for patients to ask their surgeon.

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What changed

This registry entry documents an NIH-sponsored clinical trial testing the efficacy of a decision aid pamphlet in reducing decision anxiety among low-risk thyroid cancer patients. The pamphlet provides information about three treatment options and includes questions for patients to ask their surgeon. Participants will receive the intervention before their surgical consultation and complete questionnaires at baseline, 2 weeks, 3 months, and 6 months to measure changes in decision anxiety and decision readiness.

Healthcare providers treating thyroid cancer patients and clinical investigators conducting thyroid cancer research may find this trial relevant to understanding patient decision support interventions. This registry entry does not create new compliance obligations but documents an ongoing clinical investigation into treatment decision-making for differentiated thyroid cancer.

Archived snapshot

Apr 18, 2026

GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.

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Decision Aid Efficacy in Low Risk Thyroid Cancer

N/A NCT07536412 Kind: NA Apr 17, 2026

Abstract

Low-risk thyroid cancer grows very slowly. More than 99% of patients with this cancer survive for at least 5 years. There are 3 main treatment options: remove the whole thyroid, remove just the part of the thyroid with the cancer in it, or leave the cancer in the thyroid and monitor it. Survival is similar across the 3 main treatment options. It can be difficult for patients to choose a treatment option, especially when feeling anxious about the cancer diagnosis. In this study, enrolled patients will receive a decision aid after finding out they have cancer but before meeting a surgeon. This decision aid is a pamphlet. It gives information about the treatment options and a list of questions for patients to ask their surgeons at their clinic visit. The investigators will test whether this aid changes patient decision anxiety and decision readiness.

Conditions: Differentiated Thyroid Cancer (DTC), Papillary Thyroid Microcarcinoma, Papillary Thyroid Carcinoma

Interventions: Decision Aid

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Last updated

Classification

Agency
NIH
Instrument
Notice
Legal weight
Non-binding
Stage
Final
Change scope
Minor
Document ID
NCT07536412

Who this affects

Applies to
Clinical investigators Healthcare providers
Industry sector
3254.1 Biotechnology
Activity scope
Clinical trial conduct Patient decision-making Thyroid cancer treatment
Geographic scope
United States US

Taxonomy

Primary area
Healthcare
Operational domain
Clinical Operations
Compliance frameworks
GxP
Topics
Clinical Operations Pharmaceuticals

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