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USPTO Patent Granted for Hypopigmentation Skin Treatment

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Published March 24th, 2026
Detected March 25th, 2026
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Summary

The USPTO has granted a new patent (US12582688B2) to the University of Pretoria for a topical composition containing an extract from Aspalathus linearis for treating hypopigmentation disorders of the skin. The patent covers specific compositions and methods of use for this treatment.

What changed

The United States Patent and Trademark Office (USPTO) has granted patent US12582688B2 for a topical composition designed to treat hypopigmentation. The patent, assigned to the University of Pretoria, claims a composition comprising a specific concentration of an ethanolic extract from the plant Aspalathus linearis, combined with a dermatologically acceptable carrier. This composition is intended for use in methods of preventing or treating hypopigmentary disorders of the skin by topical application.

This patent grant signifies a new intellectual property right for the University of Pretoria concerning a specific dermatological treatment. While this is a patent grant and not a regulatory rule imposing obligations on other entities, it is relevant for pharmaceutical and biotechnology companies operating in the dermatology and cosmetic sectors. Companies developing or marketing treatments for skin pigmentation disorders should be aware of this granted patent to ensure their products do not infringe upon the claims, particularly concerning the use of Aspalathus linearis extracts in topical formulations.

What to do next

  1. Review patent US12582688B2 for potential impact on existing or planned hypopigmentation treatments.
  2. Consult with legal counsel regarding intellectual property landscape for skin pigmentation therapies.

Source document (simplified)

← USPTO Patent Grants

Compositions for the treatment of hypopigmentation

Grant US12582688B2 Kind: B2 Mar 24, 2026

Assignee

University of Pretoria

Inventors

Analike Blom van Staden, Namrita Lall

Abstract

The present invention relates to a topical composition comprising a 100 μg/mL ethanolic extract from the plant Aspalathus linearis together with a dermatologically acceptable carrier for use in a method of preventing or treating a hypopigmentary disorder of skin in a subject comprising applying the topical composition to the skin of the subject. The invention further relates to methods of preventing or treating a hypopigmentary disorder of skin in a subject comprising applying the topical composition to the skin of the subject.

CPC Classifications

A61K 36/48

Filing Date

2022-06-28

Application No.

18574200

Claims

12

View original document →

Named provisions

Compositions for the treatment of hypopigmentation

Source

Analysis generated by AI. Source diff and links are from the original.

Classification

Agency
USPTO
Published
March 24th, 2026
Instrument
Notice
Legal weight
Non-binding
Stage
Final
Change scope
Minor
Document ID
US12582688B2

Who this affects

Applies to
Drug manufacturers Pharmaceutical companies
Industry sector
3254 Pharmaceutical Manufacturing 3345 Medical Device Manufacturing
Activity scope
Drug Development Intellectual Property Management
Geographic scope
United States US

Taxonomy

Primary area
Pharmaceuticals
Operational domain
Legal
Topics
Intellectual Property Medical Research

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