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USPTO Patent for Respiratory Infection Treatment with Tradipitant

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Published March 24th, 2026
Detected March 25th, 2026
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Summary

The USPTO has granted a patent to Vanda Pharmaceuticals Inc. for a method of treating lower respiratory tract infections, including those caused by COVID-19 or influenza, using the drug tradipitant. The patent, filed in 2021, details the use of this NK-1 receptor antagonist.

What changed

The United States Patent and Trademark Office (USPTO) has granted patent US12582640B2 to Vanda Pharmaceuticals Inc. This patent covers a method for treating lower respiratory tract infections, specifically mentioning those caused by coronaviruses (like COVID-19) and influenza, utilizing tradipitant, an NK-1 receptor antagonist. The patent was filed on March 24, 2021, and granted on March 24, 2026, with 20 claims.

This patent grant is primarily an intellectual property matter for Vanda Pharmaceuticals. While it signifies a new therapeutic application for tradipitant, it does not impose immediate compliance obligations on other entities. However, it may influence future market exclusivity and competitive landscape for respiratory infection treatments. Companies operating in the pharmaceutical sector, particularly those involved with respiratory treatments or NK-1 receptor antagonists, should be aware of this granted patent for competitive intelligence and potential licensing considerations.

Source document (simplified)

← USPTO Patent Grants

Treatment of lower respiratory tract infection with tradipitant

Grant US12582640B2 Kind: B2 Mar 24, 2026

Assignee

Vanda Pharmaceuticals Inc.

Inventors

Mihael H. Polymeropoulos, Christos Polymeropoulos, Vasilios Polymeropoulos, Changfu Xiao

Abstract

Disclosed herein is a method of treatment of a lower respiratory tract infection caused by, e.g., coronavirus disease (COVID-19), influenza, or other virus, comprising treatment with the NK-1 receptor antagonist, tradipitant.

CPC Classifications

A61K 31/444 A61K 31/454

Filing Date

2021-03-24

Application No.

17906861

Claims

20

View original document →

Named provisions

Treatment of lower respiratory tract infection with tradipitant

Source

Analysis generated by AI. Source diff and links are from the original.

Classification

Agency
USPTO
Published
March 24th, 2026
Instrument
Notice
Legal weight
Non-binding
Stage
Final
Change scope
Minor
Document ID
US12582640B2

Who this affects

Applies to
Drug manufacturers Pharmaceutical companies
Industry sector
3254 Pharmaceutical Manufacturing
Activity scope
Drug Development Intellectual Property Management
Geographic scope
United States US

Taxonomy

Primary area
Pharmaceuticals
Operational domain
Legal
Compliance frameworks
FDA 21 CFR Part 11 GxP
Topics
Intellectual Property Public Health

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