Ureteric Bud Kidney Tissue Engineering Compositions and Methods
Summary
The USPTO published patent application US20260098246A1 disclosing engineered ureteric bud kidney tissues and methods for making lumenized kidney tissues with spatially-controlled 3D tubular architecture. The application includes in vitro kidneys comprising nephron progenitor cells and ureteric bud cells. Inventors: Benjamin Shepherd, Alice Chen, J. William Higgins, III. Filed July 30, 2025.
What changed
The USPTO published a patent application disclosing compositions and methods for engineering ureteric bud kidney tissues and in vitro kidneys. The application covers lumenized kidney tissues with spatially-controlled 3D tubular architecture, including nephron progenitor cells and ureteric bud cells. The patent is classified under C12N biotechnology codes.
For competitors in regenerative medicine, renal disease treatment, and tissue engineering sectors, this application signals potential patent claims in the kidney tissue engineering space. Biotech and pharmaceutical companies engaged in organoid research, kidney disease therapeutics, or regenerative medicine should evaluate the scope of these claims for freedom-to-operate and R&D strategy purposes.
What to do next
- Monitor for competing patent applications in kidney tissue engineering
- Review for potential licensing or partnership opportunities
Archived snapshot
Apr 14, 2026GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.
COMPOSITIONS AND PROCESSES FOR ENGINEERING URETERIC BUD KIDNEY TISSUES AND IN-VITRO COMPOSITIONS THEREOF
Application US20260098246A1 Kind: A1 Apr 09, 2026
Inventors
Benjamin Shepherd, Alice Chen, J. William Higgins, III
Abstract
This disclosure provides compositions comprising engineered ureteric bud kidney tissues and methods of making lumenized ureteric bud kidney tissues. Also provided herein are in vitro kidneys comprising nephron progenitor cells and ureteric bud cells. Methods of making the compositions and in vitro kidneys and uses thereof are disclosed herein. In some aspects, provided herein are methods for generating a lumenized kidney tissue having a spatially-controlled 3-dimensional (3D) tubular architecture in vitro.
CPC Classifications
C12N 5/0686 B33Y 80/00 C12N 5/0018 C12N 2500/84 C12N 2501/113 C12N 2501/119 C12N 2501/13 C12N 2501/155 C12N 2501/385 C12N 2501/415 C12N 2501/727 C12N 2506/45 C12N 2513/00
Filing Date
2025-07-30
Application No.
19285431
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