Changeflow GovPing Pharma & Drug Safety Liver-Specific Viral Promoters for Gene Therapy
Routine Notice Added Final

Liver-Specific Viral Promoters for Gene Therapy

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Published March 25th, 2026
Detected April 1st, 2026
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Summary

The European Patent Office granted uniQure IP B.V. Patent EP3884049A1 covering liver-specific viral promoters for gene therapy applications. The patent protects proprietary technology for liver-targeted gene therapy vectors developed by the inventors listed. Biotechnology and pharmaceutical companies developing liver-directed gene therapies should review this grant for licensing or freedom-to-operate considerations.

What changed

EPO granted Patent EP3884049A1 to uniQure IP B.V. covering liver-specific viral promoters and methods of using the same in gene therapy. The patent application (filed under IPC classifications C12N 15/11, C07K 14/755, C12N 15/79) names eight inventors including Lubelski, du Plessis, Liu, ter Brake, and others. The designation covers all standard EPO member states including AT, BE, CH, DE, ES, FR, GB, IT, NL, and others.\n\nThis patent grant affects companies developing AAV-based or other viral vector gene therapies targeting liver tissue. Freedom-to-operate analyses should incorporate this IP position. No immediate compliance actions are required, but companies in the gene therapy space should review their pipeline technologies against this newly granted patent claims to assess potential licensing needs or design-around strategies.

Source document (simplified)

← EPO Patent Bulletin

LIVER-SPECIFIC VIRAL PROMOTERS AND METHODS OF USING THE SAME

Publication EP3884049A1 Kind: A1 Mar 25, 2026

Applicants

uniQure IP B.V.

Inventors

LUBELSKI, Jacek, DU PLESSIS, David Johannes Francois, LIU, Ying Pui, TER BRAKE, Olivier, IGLESIAS GONZALEZ, Juan Manuel, FRASER, Ross, ROBERTS, Michael

IPC Classifications

C12N 15/11 20060101AFI20200529BHEP C07K 14/755 20060101ALI20200529BHEP C12N 15/79 20060101ALI20200529BHEP

Designated States

AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR

View original document →

Named provisions

Liver-Specific Viral Promoters Methods of Using the Same

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Source

Analysis generated by AI. Source diff and links are from the original.

Classification

Agency
EPO
Published
March 25th, 2026
Instrument
Notice
Legal weight
Non-binding
Stage
Final
Change scope
Minor
Document ID
EP3884049A1

Who this affects

Applies to
Pharmaceutical companies Drug manufacturers
Industry sector
3254 Pharmaceutical Manufacturing 3254.1 Biotechnology
Activity scope
Gene Therapy Vector Development Viral Promoter Technology
Geographic scope
European Union EU

Taxonomy

Primary area
Intellectual Property
Operational domain
Legal
Topics
Biotechnology Pharmaceuticals

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