Pyrrol-2-one Compounds for Bacterial Skin Lesion Treatment
Summary
The European Patent Office published patent application EP3487495A1, granted to Unilever IP Holdings B.V. and Unilever Global IP Limited, covering 4-(4-chlorophenyl)-5-methylene-pyrrol-2-one and 5-methylene-4-(p-tolyl)pyrrol-2-one compounds for treating bacterial skin lesions. The patent is designated across 31 European states including all EU member states, with no immediate compliance obligations for third parties.
What changed
The EPO published Unilever's patent EP3487495A1 covering pyrrol-2-one compounds (4-(4-chlorophenyl)-5-methylene-pyrrol-2-one and 5-methylene-4-(p-tolyl)pyrrol-2-one) for use in treating bacterial skin lesions. Inventors include Neil Parry James, Paolo Pantalone, and Paul Williams. The patent is classified under A61K 31/4015, A61P 31/00 and is designated across 31 European states including AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, and TR.
This is a patent publication providing intellectual property protection rather than imposing regulatory compliance requirements. Pharmaceutical companies developing competing antibacterial skin treatments should review the patent scope for potential licensing considerations or to inform research into non-infringing alternatives. No immediate compliance actions are required.
Source document (simplified)
4-(4-CHLOROPHENYL)-5-METHYLENE-PYRROL-2-ONE OR 5- METHYLENE-4-(P-TOLYL)PYRROL-2-ONE FOR USE IN THE TREATMENT OF A BACTERIAL SKIN LESIONS
Publication EP3487495A1 Kind: A1 Mar 25, 2026
Applicants
Unilever IP Holdings B.V., Unilever Global IP Limited
Inventors
PARRY, Neil, James, PANTALONE, Paolo, WILLIAMS, Paul
IPC Classifications
A61K 31/4015 20060101AFI20180126BHEP A61P 31/00 20060101ALI20180126BHEP A61K 31/402 20060101ALI20180126BHEP A61K 31/40 20060101ALI20180126BHEP
Designated States
AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR
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