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Pyrrol-2-one Compounds for Bacterial Skin Lesion Treatment

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Published March 25th, 2026
Detected April 1st, 2026
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Summary

The European Patent Office published patent application EP3487495A1, granted to Unilever IP Holdings B.V. and Unilever Global IP Limited, covering 4-(4-chlorophenyl)-5-methylene-pyrrol-2-one and 5-methylene-4-(p-tolyl)pyrrol-2-one compounds for treating bacterial skin lesions. The patent is designated across 31 European states including all EU member states, with no immediate compliance obligations for third parties.

What changed

The EPO published Unilever's patent EP3487495A1 covering pyrrol-2-one compounds (4-(4-chlorophenyl)-5-methylene-pyrrol-2-one and 5-methylene-4-(p-tolyl)pyrrol-2-one) for use in treating bacterial skin lesions. Inventors include Neil Parry James, Paolo Pantalone, and Paul Williams. The patent is classified under A61K 31/4015, A61P 31/00 and is designated across 31 European states including AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, and TR.

This is a patent publication providing intellectual property protection rather than imposing regulatory compliance requirements. Pharmaceutical companies developing competing antibacterial skin treatments should review the patent scope for potential licensing considerations or to inform research into non-infringing alternatives. No immediate compliance actions are required.

Source document (simplified)

← EPO Patent Bulletin

4-(4-CHLOROPHENYL)-5-METHYLENE-PYRROL-2-ONE OR 5- METHYLENE-4-(P-TOLYL)PYRROL-2-ONE FOR USE IN THE TREATMENT OF A BACTERIAL SKIN LESIONS

Publication EP3487495A1 Kind: A1 Mar 25, 2026

Applicants

Unilever IP Holdings B.V., Unilever Global IP Limited

Inventors

PARRY, Neil, James, PANTALONE, Paolo, WILLIAMS, Paul

IPC Classifications

A61K 31/4015 20060101AFI20180126BHEP A61P 31/00 20060101ALI20180126BHEP A61K 31/402 20060101ALI20180126BHEP A61K 31/40 20060101ALI20180126BHEP

Designated States

AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR

View original document →

Named provisions

A61K 31/4015 - Pyrrol-2-one derivatives for pharmaceutical use A61P 31/00 - Anti-infectives for skin diseases

Classification

Agency
EPO
Published
March 25th, 2026
Instrument
Notice
Legal weight
Non-binding
Stage
Final
Change scope
Minor
Document ID
EP3487495A1

Who this affects

Applies to
Pharmaceutical companies Drug manufacturers
Industry sector
3254 Pharmaceutical Manufacturing
Activity scope
Pharmaceutical Patent Protection Drug Development Anti-infective Treatment
Geographic scope
European Union EU

Taxonomy

Primary area
Pharmaceuticals
Operational domain
Legal
Topics
Healthcare Intellectual Property

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