Changeflow GovPing Pharma & Drug Safety Uniform Cell Aggregate Mass Production Method
Routine Notice Added Draft

Uniform Cell Aggregate Mass Production Method

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Published March 25th, 2026
Detected April 2nd, 2026
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Summary

The European Patent Office published patent application EP4159838A1 filed by Orizuru Therapeutics, Inc. and Toyo Seikan Group Holdings, Ltd. for a mass production method of uniform-sized cell aggregates. The application was formally examined and designates all 38 EPO member states and extension countries. This biotechnological innovation has applications in regenerative medicine, drug discovery screening, and tissue engineering.

What changed

The European Patent Office published application EP4159838A1 on March 25, 2026, claiming a method for mass-producing cell aggregates of uniform size. Named inventors are YAMAURA Junji, ITO Ryo, TOYODA Taro, KONAGAYA Shuhei, and SUENAGA Ryo. The application is classified under C12M 3/00 and C12N 5/071 and designates all 38 EPO member states and extension countries.

Entities in the biotechnology, pharmaceutical, and regenerative medicine sectors should review this application to understand the technical approach disclosed and assess potential freedom-to-operate implications for their own cell aggregate production activities.

Source document (simplified)

← EPO Patent Bulletin

MASS PRODUCTION METHOD OF UNIFORM SIZE CELL AGGREGATE

Publication EP4159838A1 Kind: A1 Mar 25, 2026

Applicants

Orizuru Therapeutics, Inc., Toyo Seikan Group Holdings, Ltd.

Inventors

YAMAURA Junji, ITO Ryo, TOYODA Taro, KONAGAYA Shuhei, SUENAGA Ryo

IPC Classifications

C12M 3/00 20060101AFI20240610BHEP C12N 5/071 20100101ALI20240610BHEP

Designated States

AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR

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Source

Analysis generated by AI. Source diff and links are from the original.

Classification

Agency
EPO
Published
March 25th, 2026
Instrument
Notice
Legal weight
Non-binding
Stage
Draft
Change scope
Minor
Document ID
EP4159838A1

Who this affects

Applies to
Pharmaceutical companies Drug manufacturers Manufacturers
Industry sector
3254 Pharmaceutical Manufacturing 3254.1 Biotechnology
Activity scope
Cell Aggregate Production Regenerative Medicine Drug Discovery Screening
Geographic scope
European Union EU

Taxonomy

Primary area
Healthcare
Operational domain
Legal
Topics
Intellectual Property Biotechnology Pharmaceuticals

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