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Tri-substituted Heteroaryl Derivatives as SH2 Phosphatase Inhibitors

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Published March 25th, 2026
Detected April 1st, 2026
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Summary

The European Patent Office published patent application EP3853233A1 for tri-substituted heteroaryl derivatives designed as Src Homology-2 (SH2) phosphatase inhibitors, filed by Nikang Therapeutics, Inc. The compounds are classified under IPC A61P 35/00 indicating anti-neoplastic/anti-tumor therapeutic applications. The patent is designated for all EU member states plus associated countries.

What changed

The EPO published patent application EP3853233A1 filed by Nikang Therapeutics covering tri-substituted heteroaryl compounds as SH2 phosphatase inhibitors for anti-cancer therapeutics. The application names inventors Fu Jiping, Lou Yan, and He Yigang, with the compounds classified under multiple IPC codes including C07D 519/00, C07D 491/10, C07D 401/14, A61P 35/00, and A61K 31/5383.\n\nPatent publications do not impose compliance obligations on third parties. No action is required from pharmaceutical manufacturers or researchers working in this therapeutic area unless they are pursuing similar patent claims that may conflict with the Nikang Therapeutics intellectual property rights. Companies developing SH2 phosphatase inhibitors should review this publication for potential freedom-to-operate considerations.

Source document (simplified)

← EPO Patent Bulletin

TRI-SUBSTITUTED HETEROARYL DERIVATIVES AS SRC HOMOLOGY-2 PHOSPHATASE INHIBITORS

Publication EP3853233A1 Kind: A1 Mar 25, 2026

Applicants

Nikang Therapeutics, Inc.

Inventors

FU, Jiping, LOU, Yan, HE, Yigang

IPC Classifications

C07D 519/00 20060101AFI20200327BHEP C07D 491/10 20060101ALI20200327BHEP C07D 401/14 20060101ALI20200327BHEP A61P 35/00 20060101ALI20200327BHEP A61K 31/5383 20060101ALI20200327BHEP

Designated States

AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR

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Classification

Agency
EPO
Published
March 25th, 2026
Instrument
Notice
Legal weight
Non-binding
Stage
Final
Change scope
Minor
Document ID
EP3853233A1

Who this affects

Applies to
Pharmaceutical companies Drug manufacturers
Industry sector
3254 Pharmaceutical Manufacturing
Activity scope
Pharmaceutical Patent Filing
Geographic scope
European Union EU

Taxonomy

Primary area
Intellectual Property
Operational domain
Legal
Topics
Pharmaceuticals Healthcare

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