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Succinimide Anticonvulsants Treat Expressive Language Deficit in Autism

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Summary

USPTO granted patent US12599581B2 to AMS Therapeutics covering a pharmacological method for treating expressive language deficit in autistic humans using succinimide anticonvulsants (ethosuximide, methsuximide, phensuximide). The patent contains 10 claims with application number 18621580 filed on March 29, 2024.

Published by USPTO on changeflow.com . Detected, standardized, and enriched by GovPing. Review our methodology and editorial standards .

What changed

USPTO issued patent US12599581B2 to AMS Therapeutics covering the use of succinimide anticonvulsants (ethosuximide, methsuximide, phensuximide) for treating expressive language deficit in autistic humans. The patent protects this therapeutic method with 10 claims.

For pharmaceutical companies and autism treatment developers, this patent establishes exclusive rights to this specific treatment approach. Parties developing similar therapies should assess freedom-to-operate implications. The patent's 10-claim scope provides broad protection around the method and specific compounds disclosed.

What to do next

  1. Monitor for potential licensing or infringement issues

Archived snapshot

Apr 14, 2026

GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.

← USPTO Patent Grants

Method of treating expressive language deficit in autistic humans

Grant US12599581B2 Kind: B2 Apr 14, 2026

Assignee

AMS Therapeutics

Inventors

Charles E. Niesen

Abstract

A pharmacological method for treating the expressive language deficit in an autistic human child or adult is provided. A therapeutically effective dose of a succinimide anticonvulsant, e.g., ethosuximide, methsuximide, phensuximide, or a pharmaceutically acceptable salt thereof, is administered to a patient suffering from expressive language deficit, preferably over an extended period, e.g., six months or longer. Language gains are retained even after treatment is discontinued.

CPC Classifications

A61K 31/4015 A61P 25/08

Filing Date

2024-03-29

Application No.

18621580

Claims

10

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Last updated

Classification

Agency
USPTO
Published
April 14th, 2026
Instrument
Rule
Legal weight
Binding
Stage
Final
Change scope
Minor
Document ID
US12599581B2

Who this affects

Applies to
Pharmaceutical companies Healthcare providers
Industry sector
3254 Pharmaceutical Manufacturing
Activity scope
Patent grant Pharmaceutical method treatment Intellectual property issuance
Geographic scope
United States US

Taxonomy

Primary area
Intellectual Property
Operational domain
Legal
Compliance frameworks
GxP
Topics
Pharmaceuticals Healthcare

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