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Nonpeptide Somatostatin Type 5 Receptor Agonists and Uses Thereof

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Summary

USPTO granted patent US12600709B2 to Crinetics Pharmaceuticals covering nonpeptide somatostatin type 5 receptor agonists, methods of making the compounds, pharmaceutical compositions, and methods of using the compounds in treating conditions that benefit from somatostatin modulation. The patent includes 4 claims.

What changed

USPTO issued patent US12600709B2 to Crinetics Pharmaceuticals covering nonpeptide somatostatin type 5 receptor agonists, pharmaceutical compositions containing these compounds, and methods of using them to treat conditions that would benefit from somatostatin activity modulation. The patent names Jian Zhao, Yunfei Zhu, Shimiao Wang, Mi Chen, and Joseph Pontillo as inventors and contains 4 claims.

For pharmaceutical manufacturers and drug developers, this patent establishes intellectual property protection around somatostatin S5 receptor modulation technology. Parties developing similar somatostatin modulators or related therapeutic compounds should conduct freedom-to-operate analyses to assess potential infringement risks. The patent may also represent licensing opportunities for entities seeking access to somatostatin receptor agonist technology.

What to do next

  1. Monitor for licensing opportunities
  2. Review patent claims for freedom-to-operate analysis

Archived snapshot

Apr 14, 2026

GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.

← USPTO Patent Grants

Nonpeptide somatostatin type 5 receptor agonists and uses thereof

Grant US12600709B2 Kind: B2 Apr 14, 2026

Assignee

CRINETICS PHARMACEUTICALS, INC.

Inventors

Jian Zhao, Yunfei Zhu, Shimiao Wang, Mi Chen, Joseph Pontillo

Abstract

Described herein are compounds that are somatostatin modulators, methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds in the treatment of conditions, diseases, or disorders that would benefit from modulation of somatostatin activity.

CPC Classifications

C07D 401/04 C07D 401/14 A61P 3/10

Filing Date

2024-09-03

Application No.

18822733

Claims

4

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Last updated

Classification

Agency
USPTO
Published
April 14th, 2026
Instrument
Rule
Legal weight
Binding
Stage
Final
Change scope
Minor
Document ID
US12600709B2

Who this affects

Applies to
Pharmaceutical companies Drug manufacturers
Industry sector
3254 Pharmaceutical Manufacturing
Activity scope
Patent issuance Pharmaceutical compound development Drug therapy research
Geographic scope
United States US

Taxonomy

Primary area
Intellectual Property
Operational domain
Legal
Topics
Pharmaceuticals Healthcare

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