Shionogi Monocyclic GLP-1 Receptor Agonist Patent Application
Summary
Shionogi & Co., Ltd. filed USPTO Patent Application US20260098031A1 for a monocyclic compound demonstrating GLP-1 receptor agonist activity, along with pharmaceutically acceptable salts. The compound, classified under CPC codes C07D 405/14 and A61K 31/4439, is intended for pharmaceutical use. The application, published April 9, 2026, claims priority to the September 2023 filing date.
What changed
Shionogi & Co., Ltd. filed USPTO Application US20260098031A1, a patent application for a monocyclic compound represented by formula (I) having GLP-1 receptor agonist activity, along with pharmaceutical salts. The compound features a 5-membered heterocyclic core with varying ring nitrogens, pendant alkyl linkers, and phenyl substituents bearing halogen, cyano, alkyl, haloalkyl, alkyloxy, or haloalkyloxy groups. Claimed uses include pharmaceutical applications for metabolic disorders.
Pharmaceutical companies and researchers in the GLP-1 agonist space should monitor this application's prosecution. Competitors developing similar GLP-1 receptor modulators may need to assess design-around strategies or explore cross-licensing. The compound's monocyclic (non-peptide) structure contrasts with existing peptide-based GLP-1 therapies, potentially offering IP coverage in a distinct chemical space.
What to do next
- Monitor patent prosecution for granted claims
- Assess licensing opportunities for GLP-1 receptor agonist compound
- Review compound structure for potential design-around options
Archived snapshot
Apr 9, 2026GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.
MONOCYCLIC COMPOUND HAVING GLP-1 RECEPTOR AGONIST ACTIVITY
Application US20260098031A1 Kind: A1 Apr 09, 2026
Assignee
Shionogi & Co., Ltd.
Inventors
Yuji NISHIURA
Abstract
The present invention relates to a compound represented by the following formula (I) or a pharmaceutically acceptable salt thereof. A compound represented by formula (I): whereinA1 is C(R5) or N,A2 is C(R6) or N,A3 is C(R7) or N,R5, R6, and R7 are each independently a hydrogen atom or the like,R2 is substituted or unsubstituted alkyl or the like,-L- is a group represented by: whereinR1 is a hydrogen atom or the like,R8 is a hydrogen atom or the like,R10s are each independently cyano or the like,m is an integer of 1 to 3, andR3 is phenyl optionally substituted with substituent group F, or the like,the substituent group F: halogen, cyano, alkyl, haloalkyl, alkyloxy, and haloalkyloxy.
CPC Classifications
C07D 405/14 A61K 31/4439
Filing Date
2023-09-21
Application No.
19112482
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