RSV Vaccine Methods for Inactivating and Stabilizing Pre-F Protein
Summary
USPTO granted patent US12600750B2 to Xiamen University covering methods for inactivating respiratory syncytial virus (RSV) and stabilizing pre-F protein. The patent also covers inactivated RSV virus obtained by the method, vaccines comprising the inactivated virus, and uses of the vaccine for preventing or treating RSV infection. The patent names six inventors including Zizheng Zheng, Wei Zhang, and Ningshao Xia, with 19 claims total.
What changed
USPTO granted patent US12600750B2 to Xiamen University for methods of inactivating RSV and stabilizing pre-F protein, along with the resulting inactivated virus, vaccines, and therapeutic uses. The patent claims priority to a July 2019 filing and covers 19 claims across multiple CPC classifications including C07K 14/005 and A61K 39/155.
For pharmaceutical companies and vaccine developers working on RSV immunizations, this patent may create licensing requirements or necessitate design-around strategies to avoid infringement. Researchers in the RSV vaccine space should conduct freedom-to-operate analyses before advancing programs that may fall within the scope of these claims.
What to do next
- Monitor for patent licensing opportunities
- Review freedom-to-operate implications for RSV vaccine development
Archived snapshot
Apr 14, 2026GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.
Methods for inactivating and storing respiratory syncytial virus
Grant US12600750B2 Kind: B2 Apr 14, 2026
Assignee
Xiamen University
Inventors
Zizheng Zheng, Wei Zhang, Lujing Zhang, Yongpeng Sun, Li Chen, Ningshao Xia
Abstract
Provided are a method for inactivating respiratory syncytial virus (RSV) and stabilizing pre-F protein in RSV and inactivated RSV virus obtained thereby. Also provided are a vaccine comprising the inactivated RSV virus and a use of the vaccine in preventing or treating RSV infection or a disease related thereto.
CPC Classifications
C07K 14/005 A61K 39/155 A61K 2039/5252 A61K 2039/575 A61K 39/12 A61P 31/14 A61P 11/00 C12N 1/04 C12N 7/00 C12N 2760/18534 C12N 2760/18561 C12N 2760/18563 C12N 2760/18571
Filing Date
2019-07-08
Application No.
17258109
Claims
19
Named provisions
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Source
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