Modified S2 Subunit Coronavirus Spike Protein Patent US12600751B2
Summary
The USPTO granted patent US12600751B2 to inventors Annika Kraemer-Kuehl and Thomas Min Stephan for a modified S2 subunit of coronavirus spike protein featuring a mutation at amino acid position 865. The patent covers a recombinant avian coronavirus spike protein or fragment thereof, along with an immunogenic composition containing the modified spike protein. The patent includes 22 claims with filing date May 6, 2020.
What changed
The USPTO granted patent US12600751B2 for a recombinant avian coronavirus spike protein containing a mutation at amino acid position 865. The patent covers both the modified spike protein and immunogenic compositions incorporating it.
Pharmaceutical and biotechnology companies developing coronavirus-related vaccines or therapeutics should review this patent to assess potential licensing needs or design-around strategies for any overlapping product development.
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Apr 14, 2026GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.
Modified S2 subunit of the coronavirus spike protein
Grant US12600751B2 Kind: B2 Apr 14, 2026
Inventors
Annika Kraemer-Kuehl, Thomas Min Stephan
Abstract
A recombinant avian coronavirus spike protein or fragment thereof includes a mutation at amino acid position 865. An immunogenic composition includes an avian coronavirus with such spike protein.
CPC Classifications
C07K 14/005 A61K 39/00 A61K 2039/5258 A61K 2039/5254 A61K 39/12 C12N 2770/20052 C12N 7/00 C12N 2770/20021 C12N 2770/20022 C12N 2770/20034
Filing Date
2020-05-06
Application No.
17595124
Claims
22
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Source
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