Changeflow GovPing Pharma & Drug Safety Rifabutin Analogs for Treatment of M. abscessus...
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Rifabutin Analogs for Treatment of M. abscessus Bacterial Infections

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Summary

USPTO published patent application US20260098046A1 for new rifabutin analog compounds and pharmaceutical compositions for treating bacterial infections, with particular focus on non-tuberculous mycobacteria including M. abscessus. The application was filed on September 29, 2023 by a team of nine inventors. This is a published patent application, not a granted patent.

What changed

USPTO published patent application US20260098046A1 disclosing new rifabutin analog compounds and pharmaceutical compositions for treating bacterial infections, particularly those caused by non-tuberculous mycobacteria such as M. abscessus. The application, filed by nine named inventors including Kevin Antraigues and Sergio Lociuro, covers chemical compounds classified under CPC codes including C07D 498/22 and various A61K therapeutic formulations.

Affected parties including pharmaceutical manufacturers, biotechnology researchers, and drug developers should monitor this application's progression through examination. If granted, the patent could restrict generic competition for rifabutin analog formulations targeting M. abscessus infections, creating potential licensing or partnership opportunities for parties seeking to develop or commercialize related antibiotic therapies.

What to do next

  1. Monitor patent prosecution for grant or rejection

Archived snapshot

Apr 10, 2026

GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.

← USPTO Patent Applications

RIFABUTIN ANALOGS FOR THE TREATMENT OF DISEASE

Application US20260098046A1 Kind: A1 Apr 09, 2026

Inventors

Kevin ANTRAYGUES, Marilyne BOUROTTE, Glenn E. DALE, Olivier DEFERT, Marc GITZINGER, Sergio LOCIURO, Mathieu MAINGOT, Vincent TREBOSC, Nicolas WILLAND

Abstract

The present invention relates to compounds and pharmaceutical compositions comprising the same for the treatment, amelioration and/or prevention of disease. In some embodiments, the disease is a bacterial infection. In some embodiments, the bacterial infection is caused by one or more bacterium belonging to a genus of non-tuberculous Mycobacteria, preferably M. abscessus.

CPC Classifications

C07D 498/22 A61K 31/438 A61K 31/444 A61K 31/4545 A61K 31/496 A61K 31/541 A61K 31/55

Filing Date

2023-09-29

Application No.

19115111

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Last updated

Classification

Agency
USPTO
Published
April 9th, 2026
Instrument
Notice
Legal weight
Non-binding
Stage
Final
Change scope
Minor
Document ID
US20260098046A1

Who this affects

Applies to
Drug manufacturers Medical device makers
Industry sector
3254 Pharmaceutical Manufacturing
Activity scope
Patent application filing Chemical compound research Antibiotic development
Geographic scope
United States US

Taxonomy

Primary area
Intellectual Property
Operational domain
Regulatory Affairs
Topics
Pharmaceuticals Healthcare

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