Protein Purification Using Chemically Activated Carbon at 0.1-15 wt%
Summary
USPTO published patent application US20260098056A1 for a method of purifying proteins from fermentation-derived solutions using chemically activated carbon. The method involves contacting the solution with 0.1-15 wt% activated carbon at pH 4-12 and temperature 2-60°C. Inventors: Sebastian Schoof, Thomas Kaeding, Gabriele Iffland. Application filed October 6, 2025.
What changed
USPTO published patent application US20260098056A1 for a protein purification method using chemically activated carbon. The application claims a method for purifying fermentation-derived protein solutions by contacting with 0.1-15 wt% chemically activated carbon, adjusting pH to 4-12 and temperature to 2-60°C, then separating the carbon to obtain a clarified protein solution. The invention also covers the clarified protein solution obtainable by this method and the use of chemically activated carbon for such purification.
Companies developing protein-based products via fermentation should monitor this patent application for potential licensing implications or freedom-to-operate considerations. The specified parameters for activated carbon concentration, pH, and temperature define the scope of the claimed purification technique.
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Apr 12, 2026GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.
Protein Purification with Chemically Activated Carbon
Application US20260098056A1 Kind: A1 Apr 09, 2026
Inventors
Sebastian Schoof, Thomas Kaeding, Gabriele Iffland
Abstract
The present invention relates to the field of protein purification. The invention contemplates a method for purifying a fermentation-derived solution of a protein of interest comprising the following steps: contacting the fermentation-derived solution with chemically activated carbon in an amount ranging from 0.1 to 15 wt.-% of the solution; adjusting the pH to a value between 4 and 12, adjusting the temperature to a value between 2° C. to 60° C.; separating the chemically activated carbon from the solution; and thereby obtaining a clarified solution of the protein of interest. Moreover, it relates to a clarified solution of a protein of interest obtainable by or obtained by the method according to the invention and to the use of a chemically activated carbon for purifying a fermentation-derived solution of a protein of interest.
CPC Classifications
C07K 1/145 C07K 1/34
Filing Date
2025-10-06
Application No.
19350377
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