USPTO Patent Grant: PD-L1 Antagonist Compound
Summary
The USPTO has granted a patent (US12583839B2) to ADLAI NORTYE BIOPHARMA CO., LTD. for a PD-L1 antagonist compound and its pharmaceutical composition. The patent covers compounds of Formula (I) and their use in treating immune-related disorders.
What changed
The United States Patent and Trademark Office (USPTO) has issued patent US12583839B2, granting exclusive rights to ADLAI NORTYE BIOPHARMA CO., LTD. for a novel PD-L1 antagonist compound. The patent, which includes a compound of Formula (I), a pharmaceutical composition thereof, and a method for treating immune-related disorders, was filed on December 22, 2020, and granted on March 24, 2026. This grant signifies a new intellectual property asset for the assignee in the field of immunology and drug development.
This patent grant primarily impacts the assignee by providing market exclusivity for the patented compound. For other entities in the pharmaceutical and biotechnology sectors, this represents a new patent to consider in their freedom-to-operate analyses and competitive intelligence. While this is a patent grant and not a regulatory rule with direct compliance obligations for other companies, it is crucial for R&D, legal, and business development teams to be aware of this new intellectual property to avoid potential infringement claims and to inform their own drug development strategies.
Source document (simplified)
PD-L1 antagonist compound
Grant US12583839B2 Kind: B2 Mar 24, 2026
Assignee
ADLAI NORTYE BIOPHARMA CO., LTD.
Inventors
Zhiyong Yu, Pan Li, Beidi Xu, Yu Zhou, Wei Pang, Qiaodong Wen, Yongqiang Shi, Zhao Sun, Meng Lv
Abstract
Provided are a compound of Formula (I) and a pharmaceutical composition thereof, as well as a method for using the compounds of Formula (I) to prevent and/or treat immune-related disorders.
CPC Classifications
C07D 403/12 C07D 401/12 C07D 401/14 C07D 403/10 C07D 403/14 C07D 405/14
Filing Date
2020-12-22
Application No.
17780979
Claims
19
Named provisions
Related changes
Source
Classification
Who this affects
Taxonomy
Browse Categories
Get Pharma & Drug Safety alerts
Weekly digest. AI-summarized, no noise.
Free. Unsubscribe anytime.
Get alerts for this source
We'll email you when ChangeBridge: Patent Grants - Organic Chemistry (C07D) publishes new changes.