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USPTO Patent Grant: Theranostic Agents for PSMA Positive Cancers

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Published March 24th, 2026
Detected March 24th, 2026
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Summary

The USPTO has granted a patent (US12582728B2) to Memorial Sloan Kettering Cancer Center for theranostic agents targeting PSMA positive cancers. The patent covers compositions and methods for detecting and treating cancer using novel radiohalogenated PSMA targeting agents for diagnostic imaging and radiation therapy.

What changed

The United States Patent and Trademark Office (USPTO) has granted patent US12582728B2, titled 'Theranostic agents for PSMA positive cancers,' to Memorial Sloan Kettering Cancer Center. The patent, effective March 24, 2026, covers novel radiohalogenated PSMA targeting agents and their use in diagnostic imaging and radiation therapy for PSMA-positive cancers. The application was filed on August 28, 2020, under application number 17638512, and includes 19 claims.

This patent grant is primarily an intellectual property event and does not impose new direct compliance obligations on regulated entities. However, it may impact companies involved in the development, manufacturing, or commercialization of cancer diagnostics and therapeutics, particularly those utilizing PSMA-targeting agents. Companies operating in this space should be aware of the patented technology to ensure freedom to operate and to identify potential licensing opportunities or competitive landscapes. No specific compliance deadlines or penalties are associated with this patent grant itself.

Source document (simplified)

← USPTO Patent Grants

Theranostic agents for PSMA positive cancers

Grant US12582728B2 Kind: B2 Mar 24, 2026

Assignee

Memorial Sloan Kettering Cancer Center

Inventors

Naga Vara Kishore Pillarsetty, Teja Muralidhar Kalidindi, Sang Gyu Lee, Steven M. Larson, Jason S. Lewis, Serge Lyashchenko, Eva Burnazi

Abstract

The present disclosure provides compositions and methods for the detection and treatment of cancer. Specifically, the compositions of the present technology include novel radiohalogenated (e.g., radioiodinated) PSMA targeting agents and methods of using the same in diagnostic imaging as well as radiation therapy.

CPC Classifications

A61K 51/1045 A61K 33/243 A61K 49/0002 A61K 51/0497 A61P 35/00

Filing Date

2020-08-28

Application No.

17638512

Claims

19

View original document →

Named provisions

Theranostic agents for PSMA positive cancers Assignee Inventors Abstract CPC Classifications Filing Date Application No. Claims

Classification

Agency
USPTO
Published
March 24th, 2026
Instrument
Notice
Legal weight
Non-binding
Stage
Final
Change scope
Minor
Document ID
US12582728B2

Who this affects

Applies to
Drug manufacturers Medical device makers Pharmaceutical companies
Industry sector
3254 Pharmaceutical Manufacturing 3345 Medical Device Manufacturing
Activity scope
Cancer Diagnostics Radiation Therapy
Geographic scope
United States US

Taxonomy

Primary area
Healthcare
Operational domain
R&D
Topics
Pharmaceuticals Medical Devices

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