USPTO Patent Grant: Theranostic Agents for PSMA Positive Cancers
Summary
The USPTO has granted a patent (US12582728B2) to Memorial Sloan Kettering Cancer Center for theranostic agents targeting PSMA positive cancers. The patent covers compositions and methods for detecting and treating cancer using novel radiohalogenated PSMA targeting agents for diagnostic imaging and radiation therapy.
What changed
The United States Patent and Trademark Office (USPTO) has granted patent US12582728B2, titled 'Theranostic agents for PSMA positive cancers,' to Memorial Sloan Kettering Cancer Center. The patent, effective March 24, 2026, covers novel radiohalogenated PSMA targeting agents and their use in diagnostic imaging and radiation therapy for PSMA-positive cancers. The application was filed on August 28, 2020, under application number 17638512, and includes 19 claims.
This patent grant is primarily an intellectual property event and does not impose new direct compliance obligations on regulated entities. However, it may impact companies involved in the development, manufacturing, or commercialization of cancer diagnostics and therapeutics, particularly those utilizing PSMA-targeting agents. Companies operating in this space should be aware of the patented technology to ensure freedom to operate and to identify potential licensing opportunities or competitive landscapes. No specific compliance deadlines or penalties are associated with this patent grant itself.
Source document (simplified)
Theranostic agents for PSMA positive cancers
Grant US12582728B2 Kind: B2 Mar 24, 2026
Assignee
Memorial Sloan Kettering Cancer Center
Inventors
Naga Vara Kishore Pillarsetty, Teja Muralidhar Kalidindi, Sang Gyu Lee, Steven M. Larson, Jason S. Lewis, Serge Lyashchenko, Eva Burnazi
Abstract
The present disclosure provides compositions and methods for the detection and treatment of cancer. Specifically, the compositions of the present technology include novel radiohalogenated (e.g., radioiodinated) PSMA targeting agents and methods of using the same in diagnostic imaging as well as radiation therapy.
CPC Classifications
A61K 51/1045 A61K 33/243 A61K 49/0002 A61K 51/0497 A61P 35/00
Filing Date
2020-08-28
Application No.
17638512
Claims
19
Named provisions
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