Patent EP4626864A1: Diamide Activators by Protego Biopharma

ChangeBridge: EPO Bulletin - Organic Chemistry (C07D)

Published March 11th, 2026

Detected March 26th, 2026

Summary

The European Patent Office has published patent application EP4626864A1, titled 'Diamide Activators', filed by Protego Biopharma, Inc. The patent covers novel chemical compounds intended for use as IRE1/XBP1s activators.

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What changed

The European Patent Office (EPO) has published patent application EP4626864A1, which details "LINEAR HETEROARYL DIAMIDE IRE1/XBP1S ACTIVATORS" developed by Protego Biopharma, Inc. The application includes extensive International Patent Classification (IPC) codes related to organic chemistry and pharmaceutical compositions, indicating a focus on novel chemical entities and their potential therapeutic applications.

This publication represents the granting of a patent for specific chemical compounds and their uses. While it does not impose direct compliance obligations on regulated entities in the same way as a rule or guidance, it establishes intellectual property rights for Protego Biopharma. Companies operating in the pharmaceutical sector, particularly those involved in drug discovery and development related to IRE1/XBP1 signaling pathways, should be aware of this patent to avoid potential infringement and to inform their own research and development strategies.

Source document (simplified)

← EPO Patent Bulletin

LINEAR HETEROARYL DIAMIDE IRE1/XBP1S ACTIVATORS

Publication EP4626864A1 Kind: A1 Mar 11, 2026

Applicants

Protego Biopharma, Inc.

Inventors

LABAUDINIERE, Richard F., TAIT, Bradley Dean, QIU, Huang, PETRASSI, Hank Michael James, QIN, Bo

IPC Classifications

C07D 231/40 20060101AFI20250623BHEP C07D 285/08 20060101ALI20250623BHEP C07D 401/12 20060101ALI20250623BHEP C07D 401/14 20060101ALI20250623BHEP C07D 403/12 20060101ALI20250623BHEP C07D 405/12 20060101ALI20250623BHEP C07D 405/14 20060101ALI20250623BHEP C07D 471/04 20060101ALI20250623BHEP C07D 487/04 20060101ALI20250623BHEP C07D 491/056 20060101ALI20250623BHEP A61K 31/415 20060101ALI20250623BHEP A61K 31/433 20060101ALI20250623BHEP A61K 31/4355 20060101ALI20250623BHEP A61K 31/437 20060101ALI20250623BHEP A61K 31/4439 20060101ALI20250623BHEP A61K 31/497 20060101ALI20250623BHEP A61K 31/506 20060101ALI20250623BHEP A61P 1/00 20060101ALI20250623BHEP A61P 1/16 20060101ALI20250623BHEP A61P 3/10 20060101ALI20250623BHEP A61P 9/00 20060101ALI20250623BHEP

Designated States

AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, ME, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR

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