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Nitrogen-Containing Heterocyclic Ketones Medicinal Patent

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Published March 25th, 2026
Detected April 2nd, 2026
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Summary

The European Patent Office granted Jiangsu Hengrui Pharmaceuticals Co., Ltd. Patent EP4308549A1 for nitrogen-containing heterocyclic ketones, their preparation methods, and medicinal uses. The patent covers therapeutic applications including cardiovascular indications (heart failure, cardiovascular system diseases). The application was published March 25, 2026.

What changed

The EPO published patent application EP4308549A1 for Jiangsu Hengrui Pharmaceuticals covering nitrogen-containing heterocyclic ketone compounds (IPC classifications C07D 251/46, C07D 401/04, C07D 401/12, C07D 405/04, C07D 405/12, C07D 405/14, C07D 413/14, C07D 471/04) and their medicinal uses. The designated states include all EPC contracting states (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR). Therapeutic indications target cardiovascular conditions under A61P 9/04 and 9/10.

This is a granted patent publication rather than a regulatory requirement. Pharmaceutical companies developing competing heterocyclic ketone compounds for similar therapeutic applications should review this patent for freedom-to-operate implications. The patent provides Jiangsu Hengrui with exclusionary rights in designated European states. No compliance deadlines or penalties apply to this instrument type.

Source document (simplified)

← EPO Patent Bulletin

NITROGEN-CONTAINING HETEROCYCLIC KETONES, PREPARATION METHODS AND MEDICINAL USES THEREOF

Publication EP4308549A1 Kind: A1 Mar 25, 2026

Applicants

Jiangsu Hengrui Pharmaceuticals Co., Ltd.

Inventors

ZHU, Hugh Y., LIU, Gang, LIU, Che

IPC Classifications

C07D 251/46 20060101AFI20250422BHEP C07D 401/04 20060101ALI20250422BHEP C07D 401/12 20060101ALI20250422BHEP C07D 405/04 20060101ALI20250422BHEP C07D 405/12 20060101ALI20250422BHEP C07D 405/14 20060101ALI20250422BHEP C07D 413/14 20060101ALI20250422BHEP C07D 471/04 20060101ALI20250422BHEP C07F 7/18 20060101ALI20250422BHEP A61P 9/04 20060101ALI20250422BHEP A61P 9/10 20060101ALI20250422BHEP A61K 31/53 20060101ALI20250422BHEP

Designated States

AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR

View original document →

Named provisions

Nitrogen-Containing Heterocyclic Ketones Preparation Methods Medicinal Uses Cardiovascular Therapeutic Applications

Classification

Agency
EPO
Published
March 25th, 2026
Instrument
Notice
Legal weight
Non-binding
Stage
Final
Change scope
Minor
Document ID
EP4308549A1

Who this affects

Applies to
Pharmaceutical companies Drug manufacturers
Industry sector
3254 Pharmaceutical Manufacturing
Activity scope
Pharmaceutical Patent Protection Drug Development Intellectual Property
Geographic scope
European Union EU

Taxonomy

Primary area
Pharmaceuticals
Operational domain
Legal
Topics
Intellectual Property Healthcare

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