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EPO Patent EP4626555A1: Glutarimide Compounds for KRAS Mutant Cancer

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Published March 11th, 2026
Detected March 26th, 2026
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Summary

The European Patent Office has published patent application EP4626555A1, filed by Tiger Biotherapeutics Inc. The patent covers glutarimide-containing compounds designed as pan-KRAS-mutant degrader agents for use in treating KRAS mutant cancers. The publication date is March 11, 2026.

What changed

European Patent Application EP4626555A1, published on March 11, 2026, by Tiger Biotherapeutics Inc., details glutarimide-containing compounds intended for use as pan-KRAS-mutant degrader agents. These compounds are specifically designed for the treatment of cancers driven by KRAS mutations, a common target in oncology research.

This patent publication signifies a new development in potential cancer therapies. While it does not impose immediate compliance obligations, it is relevant for pharmaceutical companies and drug manufacturers involved in oncology research and development. Companies operating in this space should be aware of this patent as it may impact future drug development strategies and intellectual property landscapes.

Source document (simplified)

← EPO Patent Bulletin

GLUTARIMIDE-CONTAINING PAN-KRAS-MUTANT DEGRADER COMPOUNDS AND USES THEREOF

Publication EP4626555A1 Kind: A1 Mar 11, 2026

Applicants

Tiger Biotherapeutics Inc.

Inventors

LUO, Robert, LIU, Ji, HUANG, Pin, SU, Jie, FENG, Yan, LIU, Ke, FAN, Jie, HE, Wei, QIAN, Yimin

IPC Classifications

A61P 35/00 20060101AFI20240607BHEP C07D 471/04 20060101ALI20240607BHEP A61K 31/495 20060101ALI20240607BHEP

Designated States

AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, ME, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR

View original document →

Named provisions

GLUTARIMIDE-CONTAINING PAN-KRAS-MUTANT DEGRADER COMPOUNDS AND USES THEREOF

Classification

Agency
EPO
Published
March 11th, 2026
Instrument
Notice
Legal weight
Non-binding
Stage
Final
Change scope
Minor
Document ID
EP4626555A1

Who this affects

Applies to
Drug manufacturers Pharmaceutical companies
Industry sector
3254 Pharmaceutical Manufacturing
Activity scope
Drug Development Cancer Treatment
Geographic scope
European Union EU

Taxonomy

Primary area
Pharmaceuticals
Operational domain
Research & Development
Compliance frameworks
FDA 21 CFR Part 11 GxP
Topics
Cancer Treatment Drug Development

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