EPO Patent Granted for Urea Cycle Disorder Treatment
Summary
The European Patent Office (EPO) has granted patent EP3714048B1 for polynucleotides that treat urea cycle disorders. The patent, listing inventors from France and the US, was granted on March 18, 2026, and covers various European states.
What changed
The European Patent Office (EPO) has granted patent EP3714048B1, titled "POLYNUCLEOTIDES ENCODING ORNITHINE TRANSCARBAMYLASE FOR THE TREATMENT OF UREA CYCLE DISORDERS." The patent was officially granted on March 18, 2026, and lists several inventors. This grant signifies the EPO's recognition of novel polynucleotide technology for treating urea cycle disorders.
This is a patent grant, not a regulatory rule with compliance obligations for companies. It primarily impacts intellectual property strategy for pharmaceutical and biotechnology firms involved in gene therapy or the treatment of metabolic disorders. Companies operating in this space should be aware of this granted patent as it may affect their freedom to operate or potential licensing opportunities within the designated European states.
Source document (simplified)
POLYNUCLEOTIDES ENCODING ORNITHINE TRANSCARBAMYLASE FOR THE TREATMENT OF UREA CYCLE DISORDERS
Grant EP3714048B1 Kind: B1 Mar 18, 2026
Inventors
ZHUO, Zhijian, FRASSETTO, Andrea Lea, MARTINI, Paolo G.V., FINN, Patrick, PRESNYAK, Vladimir
IPC Classifications
C12N 9/10 20060101AFI20190531BHEP C12N 15/67 20060101ALI20190531BHEP A61K 48/00 20060101ALI20190531BHEP A61P 3/00 20060101ALI20190531BHEP
Designated States
AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR
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