Changeflow GovPing Pharma & Drug Safety EPO Patent Granted for Urea Cycle Disorder Trea...
Routine Notice Added Final

EPO Patent Granted for Urea Cycle Disorder Treatment

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Published March 18th, 2026
Detected March 24th, 2026
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Summary

The European Patent Office (EPO) has granted patent EP3714048B1 for polynucleotides that treat urea cycle disorders. The patent, listing inventors from France and the US, was granted on March 18, 2026, and covers various European states.

What changed

The European Patent Office (EPO) has granted patent EP3714048B1, titled "POLYNUCLEOTIDES ENCODING ORNITHINE TRANSCARBAMYLASE FOR THE TREATMENT OF UREA CYCLE DISORDERS." The patent was officially granted on March 18, 2026, and lists several inventors. This grant signifies the EPO's recognition of novel polynucleotide technology for treating urea cycle disorders.

This is a patent grant, not a regulatory rule with compliance obligations for companies. It primarily impacts intellectual property strategy for pharmaceutical and biotechnology firms involved in gene therapy or the treatment of metabolic disorders. Companies operating in this space should be aware of this granted patent as it may affect their freedom to operate or potential licensing opportunities within the designated European states.

Source document (simplified)

← EPO Patent Bulletin

POLYNUCLEOTIDES ENCODING ORNITHINE TRANSCARBAMYLASE FOR THE TREATMENT OF UREA CYCLE DISORDERS

Grant EP3714048B1 Kind: B1 Mar 18, 2026

Inventors

ZHUO, Zhijian, FRASSETTO, Andrea Lea, MARTINI, Paolo G.V., FINN, Patrick, PRESNYAK, Vladimir

IPC Classifications

C12N 9/10 20060101AFI20190531BHEP C12N 15/67 20060101ALI20190531BHEP A61K 48/00 20060101ALI20190531BHEP A61P 3/00 20060101ALI20190531BHEP

Designated States

AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR

View original document →

Named provisions

POLYNUCLEOTIDES ENCODING ORNITHINE TRANSCARBAMYLASE FOR THE TREATMENT OF UREA CYCLE DISORDERS

Source

Analysis generated by AI. Source diff and links are from the original.

Classification

Agency
EPO
Published
March 18th, 2026
Instrument
Notice
Legal weight
Non-binding
Stage
Final
Change scope
Minor
Document ID
EP3714048B1

Who this affects

Applies to
Drug manufacturers Pharmaceutical companies
Industry sector
3254 Pharmaceutical Manufacturing 3254.1 Biotechnology
Activity scope
Drug Development Gene Therapy
Geographic scope
European Union EU

Taxonomy

Primary area
Pharmaceuticals
Operational domain
Legal
Topics
Biotechnology Intellectual Property

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