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Patent Application: Phthalazine Derivatives as Pyruvate Kinase Modulators

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Published September 25th, 2025
Detected March 26th, 2026
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Summary

The USPTO has published a new patent application (US20260085061A1) for phthalazine derivatives as pyruvate kinase modulators, assigned to Sitryx Therapeutics Limited. The application was filed on September 25, 2025.

What changed

This document is a published patent application from the USPTO for a new compound, phthalazine derivatives, intended for use as pyruvate kinase modulators. The application, US20260085061A1, was filed by Sitryx Therapeutics Limited and lists David COUSIN and Oscar BARBA as inventors. The application details a compound of formula (Ia) and related aspects, with CPC classifications including C07D 401/14 and A61K 31/502.

This filing represents a new intellectual property claim and does not impose immediate regulatory obligations on other entities. However, it signals potential future developments in drug discovery and may impact the competitive landscape for companies involved in developing treatments that modulate pyruvate kinase. Compliance officers in the pharmaceutical sector should be aware of this application as it pertains to potential new therapeutic agents.

Source document (simplified)

← USPTO Patent Applications

PHTHALAZINE DERIVATIVES AS PYRUVATE KINASE MODULATORS

Application US20260085061A1 Kind: A1 Mar 26, 2026

Assignee

Sitryx Therapeutics Limited

Inventors

David COUSIN, Oscar BARBA

Abstract

The invention relates to a compound of formula (Ia): and related aspects.

CPC Classifications

C07D 401/14 A61K 31/502 C07D 403/14 C07D 491/048 C07D 498/04

Filing Date

2025-09-25

Application No.

19340382

View original document →

Named provisions

Assignee Inventors Abstract CPC Classifications Filing Date Application No.

Classification

Agency
USPTO
Published
September 25th, 2025
Instrument
Notice
Legal weight
Non-binding
Stage
Draft
Change scope
Minor
Document ID
US20260085061A1

Who this affects

Applies to
Drug manufacturers Pharmaceutical companies
Industry sector
3254 Pharmaceutical Manufacturing
Activity scope
Drug Development Intellectual Property Filing
Geographic scope
United States US

Taxonomy

Primary area
Pharmaceuticals
Operational domain
Legal
Compliance frameworks
FDA 21 CFR Part 11
Topics
Intellectual Property Drug Development

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