Changeflow GovPing Pharma & Drug Safety Methods of treating psoriasis with secukinumab
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Methods of treating psoriasis with secukinumab

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Published April 7th, 2026
Detected April 7th, 2026
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Summary

The USPTO granted patent US12594332B2 to Novartis AG covering novel regimens for treating psoriasis using secukinumab, an IL-17 antibody antagonist. The patent includes 11 claims directed to therapeutic methods employing the antibody. The patent application was filed on December 16, 2024, with inventors including Achim Guettner, Matthias Machacek, Charis Papavassilis, and Oliver Sander.

What changed

The USPTO issued patent US12594332B2 to Novartis AG on April 7, 2026, covering methods of treating psoriasis using secukinumab, an IL-17 antagonist antibody. The patent contains 11 claims and is classified under CPC codes A61K 39/3955, A61K 2039/505, and A61P 17/06. The invention disclosure describes novel dosing regimens employing secukinumab for therapeutic applications.

Pharmaceutical companies developing biosimilar IL-17 inhibitors or generic psoriasis treatments should assess whether their products or methods fall within the scope of these claims. The patent provides Novartis with exclusivity in the United States for secukinumab treatment methods, which may affect competitive entry strategies and licensing negotiations for other IL-17 targeting therapies.

What to do next

  1. Monitor for infringement of US12594332B2 patent claims covering secukinumab psoriasis treatment methods
  2. Review freedom-to-operate for any psoriasis treatment regimens involving IL-17 antagonists

Source document (simplified)

← USPTO Patent Grants

Methods of treating psoriasis with secukinumab

Grant US12594332B2 Kind: B2 Apr 07, 2026

Assignee

NOVARTIS AG

Inventors

Achim Guettner, Matthias Machacek, Charis Papavassilis, Oliver Sander

Abstract

The disclosure relates to novel regimens for treating psoriasis, which employ a therapeutically effective amount of an IL-17 antagonist, e.g., an IL-17 binding molecule, e.g., an IL-17 antibody, such as the secukinumab antibody, or an IL-17 receptor binding molecule, e.g., an IL-17 receptor antibody.

CPC Classifications

A61K 39/3955 A61K 2039/505 A61P 17/06

Filing Date

2024-12-16

Application No.

18983037

Claims

11

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Classification

Agency
USPTO
Published
April 7th, 2026
Instrument
Notice
Legal weight
Binding
Stage
Final
Change scope
Minor
Document ID
US12594332B2

Who this affects

Applies to
Pharmaceutical companies Drug manufacturers Healthcare providers
Industry sector
3254 Pharmaceutical Manufacturing
Activity scope
Patent examination IP licensing Drug development
Geographic scope
United States US

Taxonomy

Primary area
Intellectual Property
Operational domain
Regulatory Affairs
Topics
Healthcare Pharmaceuticals

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