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Methods of Treatment with Anti-Factor XI/XIa Antibodies

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Summary

The European Patent Office published Novartis AG's patent application EP3558370A2 for methods of treating conditions using anti-Factor XI/XIa antibodies. The patent names three inventors (Friedman, Khder, Lefkowitz) and covers therapeutic applications designated for all European Patent Convention states including DE, FR, GB, IT, ES, NL, and others.

What changed

The European Patent Office published EP3558370A2, granting Novartis AG exclusive rights to methods of treatment using anti-Factor XI/XIa antibodies. The patent falls under IPC classifications A61K 39/44 and A61P 7/02, covering therapeutic applications for hemostasis-related conditions.\n\nPharmaceutical and biotechnology companies developing Factor XI/XIa inhibitors or anticoagulant therapies should evaluate this patent for potential freedom-to-operate concerns in European markets. Competitors may need to seek licensing arrangements or design around the protected antibody sequences and treatment methods.

What to do next

  1. Review freedom-to-operate for Factor XI/XIa programs
  2. Monitor patent validity challenges

Archived snapshot

Apr 8, 2026

GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.

← EPO Patent Bulletin

METHODS OF TREATMENT WITH ANTI-FACTOR XI/XIA ANTIBODIES

Publication EP3558370A2 Kind: A2 Apr 01, 2026

Applicants

Novartis AG

Inventors

FRIEDMAN, Carola, KHDER, Yasser, LEFKOWITZ, Martin

IPC Classifications

A61K 39/44 20060101AFI20190619BHEP A61P 7/02 20060101ALI20190619BHEP

Designated States

AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR

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Last updated

Classification

Agency
EPO
Published
April 1st, 2026
Instrument
Notice
Legal weight
Binding
Stage
Final
Change scope
Minor
Document ID
EP3558370A2

Who this affects

Applies to
Pharmaceutical companies
Industry sector
3254 Pharmaceutical Manufacturing
Activity scope
Patent granting Therapeutic antibody IP
Geographic scope
European Union EU

Taxonomy

Primary area
Intellectual Property
Operational domain
Legal
Topics
Healthcare Pharmaceuticals

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