USPTO Patent Application: Modified Coronavirus Spike Antigen Protein
Summary
The USPTO has published a patent application (US20260083836A1) for a modified coronavirus spike antigen protein. The application describes a protein designed to suppress cell membrane fusion ability and improve safety by modifying cleavage sites, aiming to enhance vaccine efficacy and antibody production.
What changed
This document is a USPTO patent application (US20260083836A1) filed on June 15, 2023, titled 'Modified coronavirus spike antigen protein and uses thereof.' The application details a modified spike antigen protein that aims to improve safety by altering two cleavage sites, thereby suppressing cell membrane fusion ability. It also claims that vaccines incorporating this antigen protein can induce a high number of neutralizing antibodies, inhibiting viral invasion and proliferation.
As this is a patent application, it does not impose direct compliance obligations on regulated entities. However, it is relevant for pharmaceutical companies and drug manufacturers involved in vaccine development, particularly those working on coronavirus-related therapeutics. Compliance officers in these sectors should be aware of emerging intellectual property in this area, which could impact future product development and market exclusivity.
Source document (simplified)
MODIFIED CORONAVIRUS SPIKE ANTIGEN PROTEIN AND USES THEREOF
Application US20260083836A1 Kind: A1 Mar 26, 2026
Inventors
Jong-Won OH, Hae-Gwang JUNG, Han Young SEO
Abstract
There is a modified coronavirus spike antigen protein and uses therefor. The spike antigen protein of coronavirus exhibits suppression of cell membrane fusion ability and improves safety by modifying two protein cleavage sites present in the coronavirus spike protein. In addition, inoculation with a vaccine having the antigen protein induces production of a large number of neutralizing antibodies to inhibit invasion of coronavirus into cells, thereby suppressing viral proliferation.
CPC Classifications
A61K 39/215 A61P 37/04 C07K 14/005
Filing Date
2023-06-15
Application No.
18872553
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