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USPTO Patent Application: Modified Coronavirus Spike Antigen Protein

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Published June 15th, 2023
Detected March 26th, 2026
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Summary

The USPTO has published a patent application (US20260083836A1) for a modified coronavirus spike antigen protein. The application describes a protein designed to suppress cell membrane fusion ability and improve safety by modifying cleavage sites, aiming to enhance vaccine efficacy and antibody production.

What changed

This document is a USPTO patent application (US20260083836A1) filed on June 15, 2023, titled 'Modified coronavirus spike antigen protein and uses thereof.' The application details a modified spike antigen protein that aims to improve safety by altering two cleavage sites, thereby suppressing cell membrane fusion ability. It also claims that vaccines incorporating this antigen protein can induce a high number of neutralizing antibodies, inhibiting viral invasion and proliferation.

As this is a patent application, it does not impose direct compliance obligations on regulated entities. However, it is relevant for pharmaceutical companies and drug manufacturers involved in vaccine development, particularly those working on coronavirus-related therapeutics. Compliance officers in these sectors should be aware of emerging intellectual property in this area, which could impact future product development and market exclusivity.

Source document (simplified)

← USPTO Patent Applications

MODIFIED CORONAVIRUS SPIKE ANTIGEN PROTEIN AND USES THEREOF

Application US20260083836A1 Kind: A1 Mar 26, 2026

Inventors

Jong-Won OH, Hae-Gwang JUNG, Han Young SEO

Abstract

There is a modified coronavirus spike antigen protein and uses therefor. The spike antigen protein of coronavirus exhibits suppression of cell membrane fusion ability and improves safety by modifying two protein cleavage sites present in the coronavirus spike protein. In addition, inoculation with a vaccine having the antigen protein induces production of a large number of neutralizing antibodies to inhibit invasion of coronavirus into cells, thereby suppressing viral proliferation.

CPC Classifications

A61K 39/215 A61P 37/04 C07K 14/005

Filing Date

2023-06-15

Application No.

18872553

View original document →

Classification

Agency
USPTO
Published
June 15th, 2023
Instrument
Notice
Legal weight
Non-binding
Stage
Final
Change scope
Minor
Document ID
US20260083836A1

Who this affects

Applies to
Drug manufacturers Pharmaceutical companies
Industry sector
3254 Pharmaceutical Manufacturing 3254.1 Biotechnology
Activity scope
Vaccine Development
Geographic scope
United States US

Taxonomy

Primary area
Pharmaceuticals
Operational domain
Research & Development
Topics
Vaccines Biotechnology

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