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Pharmaceutical Compositions Comprising Maralixibat and Uses Thereof

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Published April 2nd, 2026
Detected April 2nd, 2026
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Summary

The USPTO published patent application US20260090993A1 by Mirum Pharmaceuticals, Inc. for pharmaceutical compositions comprising maralixibat as an active ingredient. The application covers the use of these compositions as solid dosage drug products for treating cholestatic pruritus and cholestatic liver disease. The application was filed on April 9, 2025, and contains 8 CPC classifications related to drug formulations.

What changed

The USPTO published patent application US20260090993A1, filed by Mirum Pharmaceuticals, Inc. and inventor Parag VED, covering pharmaceutical compositions comprising maralixibat or a pharmaceutically acceptable salt. The application claims solid dosage drug products and methods of using these compositions for treating cholestatic pruritus and cholestatic liver disease. The patent contains 8 CPC classifications covering drug formulations (A61K 9/2009 series), the active compound (A61K 31/4995), and various excipients (A61K 47/10, 47/12, 47/183, 47/22).

This patent publication is informational and does not impose compliance requirements on third parties. Pharmaceutical companies developing maralixibat formulations or competing products should review the claimed compositions and uses to assess potential freedom-to-operate considerations. No immediate action is required; the application represents potential future IP claims that may affect product development strategies.

Source document (simplified)

← USPTO Patent Applications

PHARMACEUTICAL COMPOSITIONS COMPRISING MARALIXIBAT AND USES THEREOF

Application US20260090993A1 Kind: A1 Apr 02, 2026

Assignee

Mirum Pharmaceuticals, Inc.

Inventors

Parag VED

Abstract

The invention relates to a pharmaceutical composition comprising maralixibat, or a pharmaceutically acceptable salt thereof, as the active ingredient. The invention further relates to the use of the pharmaceutical composition as a solid dosage drug product. The invention also relates to the use of the pharmaceutical composition and the solid dosage drug product described herein for treating cholestatic pruritus and cholestatic liver disease.

CPC Classifications

A61K 9/2054 A61K 9/2009 A61K 9/2031 A61K 31/4995 A61K 47/10 A61K 47/12 A61K 47/183 A61K 47/22

Filing Date

2025-04-09

Application No.

19174281

View original document →

Named provisions

Pharmaceutical Compositions Solid Dosage Drug Product Cholestatic Pruritus Treatment Cholestatic Liver Disease Treatment

Classification

Agency
USPTO
Published
April 2nd, 2026
Instrument
Notice
Legal weight
Non-binding
Stage
Final
Change scope
Minor
Document ID
US20260090993A1

Who this affects

Applies to
Pharmaceutical companies Drug manufacturers
Industry sector
3254 Pharmaceutical Manufacturing 3254.1 Biotechnology
Activity scope
Pharmaceutical Patent Claims Drug Composition Formulations Therapeutic Methods
Geographic scope
United States US

Taxonomy

Primary area
Intellectual Property
Operational domain
Legal
Topics
Pharmaceuticals Healthcare

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