Changeflow GovPing Pharma & Drug Safety Human CD3 Binding Antibody Patent
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Human CD3 Binding Antibody Patent

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Published March 25th, 2026
Detected April 1st, 2026
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Summary

The European Patent Office published patent application EP3757129A1 for Merus B.V., covering a human CD3 binding antibody. The application, filed by inventors Bakker and van Loo, claims priority dates back to October 2020 and designates 31 European states. This publication makes the patent claims publicly available, establishing priority dates and technical scope for the CD3-targeted antibody therapeutic.

What changed

EPO published Merus B.V.'s patent application EP3757129A1 for a human CD3 binding antibody (C07K 16/28) with therapeutic applications in cancer treatment (A61P 35/00, A61P 35/02). The patent names inventors Bakker and van Loo, with IPC classifications indicating antibody therapeutics and medicinal preparations. Designated states include all major European markets (DE, FR, GB, IT, ES, NL, BE, CH, etc.).

Pharmaceutical companies developing competing CD3-targeted antibodies should review the claims for potential freedom-to-operate concerns. Research institutions and biotech firms conducting similar work should assess whether their technologies may infringe the published claims. The publication establishes priority dates from October 2020, which may affect earlier patent filings by competitors.

What to do next

  1. Review patent claims EP3757129A1 for freedom-to-operate analysis if developing CD3-targeted antibodies
  2. Assess whether existing antibody development programs may conflict with the published scope
  3. Monitor for patent grant and subsequent opposition period

Source document (simplified)

← EPO Patent Bulletin

HUMAN CD3 BINDING ANTIBODY

Publication EP3757129A1 Kind: A1 Mar 25, 2026

Applicants

Merus B.V.

Inventors

BAKKER, Alexander Berthold Hendrik, VAN LOO, Pieter Fokko

IPC Classifications

C07K 16/28 20060101AFI20201028BHEP A61K 39/395 20060101ALI20201028BHEP A61P 35/00 20060101ALI20201028BHEP A61P 35/02 20060101ALI20201028BHEP A61K 39/00 20060101ALN20201028BHEP

Designated States

AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR

View original document →

Named provisions

Human CD3 Binding Antibody Designated States

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Classification

Agency
EPO
Published
March 25th, 2026
Instrument
Notice
Legal weight
Non-binding
Stage
Final
Change scope
Minor
Document ID
EP3757129A1

Who this affects

Applies to
Pharmaceutical companies Drug manufacturers Healthcare providers
Industry sector
3254 Pharmaceutical Manufacturing 3254.1 Biotechnology
Activity scope
Pharmaceutical Patent Publication Antibody Therapeutics IP
Geographic scope
European Union EU

Taxonomy

Primary area
Pharmaceuticals
Operational domain
Legal
Topics
Intellectual Property Healthcare

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