Human CD3 Binding Antibody Patent
Summary
The European Patent Office published patent application EP3757129A1 for Merus B.V., covering a human CD3 binding antibody. The application, filed by inventors Bakker and van Loo, claims priority dates back to October 2020 and designates 31 European states. This publication makes the patent claims publicly available, establishing priority dates and technical scope for the CD3-targeted antibody therapeutic.
What changed
EPO published Merus B.V.'s patent application EP3757129A1 for a human CD3 binding antibody (C07K 16/28) with therapeutic applications in cancer treatment (A61P 35/00, A61P 35/02). The patent names inventors Bakker and van Loo, with IPC classifications indicating antibody therapeutics and medicinal preparations. Designated states include all major European markets (DE, FR, GB, IT, ES, NL, BE, CH, etc.).
Pharmaceutical companies developing competing CD3-targeted antibodies should review the claims for potential freedom-to-operate concerns. Research institutions and biotech firms conducting similar work should assess whether their technologies may infringe the published claims. The publication establishes priority dates from October 2020, which may affect earlier patent filings by competitors.
What to do next
- Review patent claims EP3757129A1 for freedom-to-operate analysis if developing CD3-targeted antibodies
- Assess whether existing antibody development programs may conflict with the published scope
- Monitor for patent grant and subsequent opposition period
Source document (simplified)
HUMAN CD3 BINDING ANTIBODY
Publication EP3757129A1 Kind: A1 Mar 25, 2026
Applicants
Merus B.V.
Inventors
BAKKER, Alexander Berthold Hendrik, VAN LOO, Pieter Fokko
IPC Classifications
C07K 16/28 20060101AFI20201028BHEP A61K 39/395 20060101ALI20201028BHEP A61P 35/00 20060101ALI20201028BHEP A61P 35/02 20060101ALI20201028BHEP A61K 39/00 20060101ALN20201028BHEP
Designated States
AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR
Named provisions
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