KRAS Modulating Compounds
Summary
USPTO published patent application US20260098049A1 for KRAS modulating compounds useful as KRAS inhibitors. The application covers compounds, methods of making and using them, and pharmaceutical compositions. Filed August 11, 2025, with 19 inventors listed.
What changed
USPTO published patent application US20260098049A1 for KRAS modulating compounds useful as KRAS inhibitors, filed August 11, 2025. The application discloses compounds and pharmaceutical compositions, listing 19 inventors including researchers from the pharmaceutical sciences field.
Pharmaceutical companies and researchers working on RAS-family oncology targets should monitor this application's progression. If granted, the patent would confer exclusive rights to the claimed KRAS modulators and associated methods, potentially affecting freedom-to-operate for competing programs in the targeted therapy space.
What to do next
- Monitor patent prosecution progress
- Review claims for freedom-to-operate analysis
- Assess competitive landscape impact
Archived snapshot
Apr 10, 2026GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.
KRAS MODULATING COMPOUNDS
Application US20260098049A1 Kind: A1 Apr 09, 2026
Inventors
Eda Y. Canales, Christopher T. Clark, Zhimin Du, Yassin M.A. Elbatrawi, Quinn B. Greven, Tezcan Guney, Darryl Kato, Henok H. Kinfe, Irene N. Kiburu, Scott E. Lazerwith, Thomas C.J. Mies, Christopher J. Swank, Rhiannon Thomas-Tran, Guanghu Tong, William J. Watkins, Wilian Augusto Cortopassi Coelho
Abstract
Provided herein are compounds, and pharmaceutically acceptable salts thereof, useful as KRAS inhibitors, methods of making and using the same (singly or in combination with additional agents), and pharmaceutical compositions thereof.
CPC Classifications
C07D 519/00 A61K 31/553
Filing Date
2025-08-11
Application No.
19296626
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