Carbonated Aerosol Skin Preparation Patent

ChangeBridge: Patent Grants - Pharma (A61K)

Published March 31st, 2026

Detected March 31st, 2026

Summary

USPTO granted Patent US12589110B2 to KAO Corporation for a carbonated aerosol external preparation for skin containing heparinoid, water-soluble polymer, water, and carbon dioxide gas propellant. The patent contains 16 claims and was filed on October 1, 2021.

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What changed

USPTO granted Patent US12589110B2 to KAO Corporation for a carbonated aerosol skin preparation comprising a stock solution with heparinoid (component A), water-soluble polymer including hydroxypropylmethylcellulose or acrylic acid/alkyl(meth)acrylate copolymer (component B, 0.05-5.0% by mass), water (component C), and carbon dioxide gas propellant (component D). The formulation has a pH of 4.0-7.0 upon discharge. The patent covers CPC classifications A61K 31/737 and A61K 9/124.

This is a routine patent grant notification with no immediate compliance requirements. Pharmaceutical companies developing topical or aerosol-based dermatological products should review the patent claims to assess potential freedom-to-operate concerns. There are no specified deadlines, penalties, or required actions associated with this patent grant.

Source document (simplified)

← USPTO Patent Grants

Carbonated aerosol external preparation for skin

Grant US12589110B2 Kind: B2 Mar 31, 2026

Assignee

KAO CORPORATION

Inventors

Ryoko Harada, Tadashi Miyazaki, Megumi Matsuoka

Abstract

A carbonated aerosol external preparation for skin, including a stock solution containing the following components (A) to (C), and a propellant containing the following component (D): (A) heparinoid, (B) water-soluble polymer, (C) water, and (D) carbon dioxide gas. The carbonated aerosol external preparation for skin has a pH immediately after discharge of 4.0 or more and 7.0 or less. The component (B) includes one or more selected from the group consisting of hydroxypropylmethylcellulose and acrylic acid/alkyl (meth)acrylate copolymer. A content of the component (B) in the stock solution is from 0.05 to 5.0% by mass, based on a total mass of the stock solution.